Results 281 to 290 of about 2,578,136 (352)

Immunochemical comparison of synaptic plasma membrane and synaptic vesicle membrane antigens

Journal of Neurocytology, 1977
A synaptic vesicle fraction and a synaptic plasma membrane fraction obtained after subfractionation of synaptosomes from chick forebrain have been used to produce antisera in rabbits. Immunofluorescence histology with the two antisera revealed that they reacted strongly with synaptic terminal regions present in the chick forebrain, cerebellum and ...
P R, Howe, E M, Fenwick, J A, Rostas, B G, Livett   +3 more
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Identification of a local anesthetic binding site in nicotinic post-synaptic membranes isolated from Torpedo marmorata electric tissue.

Molecular Pharmacology, 1979
Studies are presented of the interaction of aromatic amine noncompetitive antagonists with the receptor-rich (post-synaptic) membranes isolated from Torpedo marmorata electric organ.
Elizabeth K. Krodel, Robert A. Beckman, Jonathan B. Cohen   +2 more
semanticscholar   +1 more source

Dynamics of synaptic vesicle fusion and membrane retrieval in synaptic terminals

Nature, 1994
Communication among neurons occurs at specialized synaptic junctions, where neurotransmitter is released via calcium-dependent exocytosis from the synaptic terminal of the presynaptic cell onto the postsynaptic target neuron. Here we exploit the unique properties of giant synaptic terminals of bipolar neurons from goldfish retina to establish the ...
H, von Gersdorff, G, Matthews
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Proteins of the synaptic membrane

Neurochemical Research, 1977
The purpose of this communication is to provide a survey of contempory information concerning the composition, disposition, and functional significance of proteins in or on synaptic membranes derived from rat brain synaptosomes. Special emphasis is placed on their content of glycoproteins, fibrous proteins, proteins susceptible to rapid phosphorylation
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Synaptic membrane antigens: detection and characterization

Journal of Neuroscience Methods, 1980
Analysis of the antigenic components of synaptic membranes presents several problems caused by detergents required to solubilize the proteins. These problems involve detection of the reaction between antibodies and proteins in the detergent extract as well as characterization of the individual antigens after further purification.
S P, Mahadik, A, Korenovsky, Y Y, Huang, L, Graf, M M, Rapport   +4 more
openaire   +2 more sources

Selforganization of a membrane in synaptic geometry

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1989
The self-organization of mobile membrane proteins in a synaptic structure is computed. The model of dissipative condensation is used which takes into account the intermolecular interactions due to electrical channel currents and electrophoretic charges as they occur in a leaky membrane. An instability of the homogeneous fluid mosaic of charged channels
openaire   +2 more sources

Fractionation of synaptic membranes with sodium diatrizoate

Analytical Biochemistry, 1976
Abstract Synaptic membranes from rat brain cortex were obtained in high yield by a short procedure based on osmotic shock of synaptosomes (P 2 B fraction) followed by fractionation of the membranes on a discontinuous gradient of sodium diatrizoate. Four membrane fractions and the mitochondrial pellet were characterized by morphology, an eight-enzyme ...
H, Tamir, S P, Mahadik, M M, Rapport
openaire   +2 more sources

Ultrastructure of the Membrane of Synaptic Vesicles

Nature, 1967
INVESTIGATIONS by Whittaker and Sheridan1 on permanganate fixed preparations of isolated synaptic vesicles have recently confirmed that the membrane of such organelles has the structure of a “unit membrane”2, but have also indicated that in this case the classical model should be corrected in order to take into account the results obtained on negative ...
openaire   +2 more sources

Isolation of Synaptosomes, Synaptic Plasma Membranes, and Synaptic Junctional Complexes

2016
Isolation of synaptic nerve terminals or synaptosomes provides an opportunity to study the process of neurotransmission at many levels and with a variety of approaches. For example, structural features of the synaptic terminals and the organelles within them, such as synaptic vesicles and mitochondria, have been elucidated with electron microscopy. The
Mary L, Michaelis, Lei, Jiang, Elias K, Michaelis   +2 more
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Junctional ultrastructure in isolated synaptic membranes

Journal of Neurocytology, 1975
The ultrastructure of synaptic junctions in whole brain tissue and isolated synaptic membranes has been compared. Type 1 junctions are present in the isolated membranes,readily identified by the presence of dense-staining material associated with the postsynaptic membrane, but the dense projections present at the presynaptic membrane in intact tissue ...
A I, Matus, B B, Walters, D H, Jones
openaire   +2 more sources