Results 291 to 300 of about 2,578,136 (352)
Some of the next articles are maybe not open access.
Membranes in Synaptic Function
Hospital Practice, 1974Many significant details have emerged from studies of the membranes involved in neural transmission. It has been found that acetylcholine—and perhaps other neurohumors—is bound in tiny membranous vesicles concentrated at the terminals of nerve cells. These vesicles release their contents in discrete quanta by a mechanism that appears to be akin to the ...
openaire +1 more source
THE FIXATION OF TETANUS TOXIN BY SYNAPTIC MEMBRANES
Journal of Neurochemistry, 1968Abstract—The ability of subfractions of disrupted synaptosomes to bind tetanus toxin has been studied. Synaptic vesicles had little toxin‐fixing capacity, but a fraction believed on morphological appearance and enzymic composition to be rich in external synaptosome membranes had a toxin‐fixing capacity about 10 times that of the synaptic vesicles and ...
J, Mellanby, V P, Whittaker
openaire +2 more sources
Submicroscopic Organization of Post-synaptic Membranes
Nature, 1959BECAUSE of their importance in the transmission of impulses, the postsynaptic membranes have been repeatedly investigated by histochemical and electron-microscopical methods. Very little is known, however, about the internal organization of these structures. It was felt that polarization microscopy might give useful information in this respect.
openaire +2 more sources
Structural Modifications of Gangliosides in Synaptic Membranes
1980It has been hypothesized that neuronal gangliosides are involved in receptors for biogenic amines (1–3) and certain neuro-toxins (4,5), and it is generally, although not universally (6), believed that, in the central nervous system, gangliosides are to be found concentrated in synaptic membranes.
K C, Leskawa, A, Rosenberg
openaire +2 more sources
Molecular Pharmacology, 1977
The effects of ions, detergents, and enzymes on γ-aminobutyric acid (GABA) binding to synaptic receptor sites in membranes of rat brain in the absence of sodium is contrasted with influences on sodium-dependent GABA binding.
S. Enna, S. Snyder
semanticscholar +1 more source
The effects of ions, detergents, and enzymes on γ-aminobutyric acid (GABA) binding to synaptic receptor sites in membranes of rat brain in the absence of sodium is contrasted with influences on sodium-dependent GABA binding.
S. Enna, S. Snyder
semanticscholar +1 more source
Journal of Neurochemistry, 1987
Abstract: Rats were administered [3H]fucose by intracranial injection and synaptic membranes (SMs) isolated 18 h later. Oligosaccharides associated with SM glycoproteins were prepared by hydrazinolysis and analyzed by a combination of affinity chromatography on concanavalin A (Con A)‐agarose, ion‐exchange chromatography on DEAE‐celluiose, and gel ...
D, Stanojev, J W, Gurd
openaire +2 more sources
Abstract: Rats were administered [3H]fucose by intracranial injection and synaptic membranes (SMs) isolated 18 h later. Oligosaccharides associated with SM glycoproteins were prepared by hydrazinolysis and analyzed by a combination of affinity chromatography on concanavalin A (Con A)‐agarose, ion‐exchange chromatography on DEAE‐celluiose, and gel ...
D, Stanojev, J W, Gurd
openaire +2 more sources
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1976
A procedure is described for the isolation of synaptic membrane fragments that retain such functionally important proteins as acetylcholine receptors, acetylcholinesterase, 3',5'-cyclic nucleotide phosphodiesterase, and (Na+ + K+)-ATPase. The method is based on the observation, made in brain slices, that junctional membranes are more resistant to ...
T, Bartfai +3 more
openaire +2 more sources
A procedure is described for the isolation of synaptic membrane fragments that retain such functionally important proteins as acetylcholine receptors, acetylcholinesterase, 3',5'-cyclic nucleotide phosphodiesterase, and (Na+ + K+)-ATPase. The method is based on the observation, made in brain slices, that junctional membranes are more resistant to ...
T, Bartfai +3 more
openaire +2 more sources
Naunyn-Schmiedeberg's Archives of Pharmacology, 1979
Although it is agreed that the bilayer lipid region of neural membranes is a principle site of action of general anesthetics, the nature of the action is somewhat controversial, and may depend on the structure of the membranes and the concentration of the anesthetics.
openaire +2 more sources
Although it is agreed that the bilayer lipid region of neural membranes is a principle site of action of general anesthetics, the nature of the action is somewhat controversial, and may depend on the structure of the membranes and the concentration of the anesthetics.
openaire +2 more sources
Synaptic Membranes Bend to the Will of a Neurotoxin
Science, 2005In their Perspective, Zimmerberg and Chernomordik discuss the study by Rigoni et al. In the same issue that shows how the lipid products of a phospholipase present in snake venom reproduce the known paralytic effect of the lipase itself on presynaptic action in the neuromuscular junction.
Joshua Zimmerberg +1 more
openaire +1 more source
Synaptic amplification by active membrane in dendritic spines
Brain Research, 1985The suspected functional role of dendritic spines as loci of neuronal plasticity (possibly memory and learning) is greatly enriched when active membrane properties are assumed at the spine head. Computations with reasonable electrical and structural parameter values (corresponding to an optimal range for spine stem resistance) show that an active spine
J P, Miller, W, Rall, J, Rinzel
openaire +2 more sources