Results 41 to 50 of about 2,712,162 (368)
Biochemistry and Biophysics Reports, 2021 Riluzole (2-amino-6-(trifluoromethoxy)benzothiazole) is a drug known for its inhibitory effect on glutamatergic transmission and its anti-nociceptive and anti-allodynic effects in neuropathic pain rat models.
Ryo Taiji +6 more
doaj +1 more source
Approaches and Limitations in the Investigation of Synaptic Transmission and Plasticity
Frontiers in Synaptic Neuroscience, 2019 The numbers and strengths of synapses in the brain change throughout development, and even into adulthood, as synaptic inputs are added, eliminated, and refined in response to ongoing neural activity.
S. Glasgow +4 more
semanticscholar +1 more source
mGluR-dependent synaptic plasticity in drug-seeking.
Frontiers in Pharmacology, 2012 A primary feature of drug addiction is the compulsive use despite negative consequences. A general consensus is emerging on the capacity of addictive substances to co-opt synaptic transmission and synaptic plasticity in brain circuits which are involved ...
Camilla eBellone +3 more
doaj +1 more source
Differential localization of glutamate receptor subunits at the drosophila neuromuscular junction [PDF]
, 2004 The subunit composition of postsynaptic neurotransmitter receptors is a key determinant of synaptic physiology. Two glutamate receptor subunits, Drosophila glutamate receptor IIA (DGluRIIA) and DGluRIIB, are expressed at the Drosophila neuromuscular ...
Allen, Marcus James +4 more
core +1 more source
Neuromorphic Learning towards Nano Second Precision [PDF]
, 2013 Temporal coding is one approach to representing information in spiking neural networks. An example of its application is the location of sounds by barn owls that requires especially precise temporal coding. Dependent upon the azimuthal angle, the arrival
Meier, Karlheinz +3 more
core +1 more source
Journal of Neuroscience, 2016 Estradiol (E2) acutely potentiates glutamatergic synaptic transmission in the hippocampus of both male and female rats. Here, we investigated whether E2-induced synaptic potentiation occurs via presynaptic and/or postsynaptic mechanisms and which ...
J. G. Oberlander, C. Woolley
semanticscholar +1 more source
Synaptic Transmission: Kinetics of synaptic-vesicle recycling [PDF]
Current Biology, 1995 The kinetics of different steps in synaptic-vesicle recycling, including exocytosis, internalization and repriming, have recently been estimated in various types of living cell.
William J. Betz, Ling-Gang Wu
openaire +3 more sources
eLife, 2017 Synaptic vesicle release properties vary between neuronal cell types, but in most cases the molecular basis of this heterogeneity is unknown. Here, we compare in vivo synaptic properties of two neuronal classes in the C.
Donovan Ventimiglia, Cornelia I Bargmann
doaj +1 more source
Presynaptic Rac1 controls synaptic strength through the regulation of synaptic vesicle priming
eLife, 2022 Synapses contain a limited number of synaptic vesicles (SVs) that are released in response to action potentials (APs). Therefore, sustaining synaptic transmission over a wide range of AP firing rates and timescales depends on SV release and replenishment.
Christian Keine +9 more
doaj +1 more source
NPY-mediated synaptic plasticity in the extended amygdala prioritizes feeding during starvation
Nature CommunicationsEfficient control of feeding behavior requires the coordinated adjustment of complex motivational and affective neurocircuits. Neuropeptides from energy-sensing hypothalamic neurons are potent feeding modulators, but how these endogenous signals shape ...
Stephan Dodt +7 more
doaj +1 more source