Results 21 to 30 of about 1,906,626 (299)

Synaptic transfer of dynamic motion information between identified neurons in the visual system of the blowfly [PDF]

open access: yes, 2003
Warzecha A-K, Kurtz R, Egelhaaf M. Synaptic transfer of dynamic motion information between identified neurons in the visual system of the blowfly. Neuroscience.
Egelhaaf, Martin ; https://orcid.org/   +2 more
core   +1 more source

Membrane palmitoylated protein 2 is a synaptic scaffold protein required for synaptic SK2-containing channel function

open access: yeseLife, 2016
Mouse CA1 pyramidal neurons express apamin-sensitive SK2-containing channels in the post-synaptic membrane, positioned close to NMDA-type (N-methyl-D-aspartate) glutamate receptors.
Gukhan Kim   +8 more
doaj   +1 more source

Differential synaptic mechanism underlying the neuronal modulation of prefrontal cortex, amygdala, and hippocampus in response to chronic postsurgical pain with or without cognitive deficits in rats

open access: yesFrontiers in Molecular Neuroscience, 2022
Chronic Postsurgical Pain (CPSP) is well recognized to impair cognition, particularly memory. Mounting evidence suggests anatomic and mechanistic overlap between pain and cognition on several levels.
Zhen Li   +5 more
doaj   +1 more source

Adenosine A1 receptor activation mediates the developmental shift at layer 5 pyramidal cell synapses and is a determinant of mature synaptic strength [PDF]

open access: yes, 2013
During the first postnatal month glutamatergic synapses between layer 5 pyramidal cells in the rodent neocortex switch from an immature state exhibiting high probability of neurotransmitter release, large unitary amplitude and synaptic depression to a ...
Richardson, Magnus J. E.   +2 more
core   +1 more source

Oxytocin Regulates Synaptic Transmission in the Sensory Cortices in a Developmentally Dynamic Manner

open access: yesFrontiers in Cellular Neuroscience, 2021
The development and stabilization of neuronal circuits are critical to proper brain function. Synapses are the building blocks of neural circuits. Here we examine the effects of the neuropeptide oxytocin on synaptic transmission in L2/3 pyramidal neurons
Jing Zhang   +8 more
doaj   +1 more source

Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity [PDF]

open access: yes, 2012
Synaptic long-term potentiation (LTP) at spinal neurons directly communicating pain-specific inputs from the periphery to the brain has been proposed to serve as a trigger for pain hypersensitivity in pathological states.
Todd, A. J.   +103 more
core   +2 more sources

Bidirectional Dysregulation of AMPA Receptor-Mediated Synaptic Transmission and Plasticity in Brain Disorders

open access: yesFrontiers in Synaptic Neuroscience, 2020
AMPA receptors (AMPARs) are glutamate-gated ion channels that mediate the majority of fast excitatory synaptic transmission throughout the brain. Changes in the properties and postsynaptic abundance of AMPARs are pivotal mechanisms in synaptic plasticity,
Hongyu Zhang, Clive R. Bramham
doaj   +1 more source

Adenosine-mediated modulation of ventral horn interneurons and spinal motoneurons in neonatal mice [PDF]

open access: yes, 2015
The authors are grateful for support from the Wellcome Trust.Neuromodulation allows neural networks to adapt to varying environmental and biomechanical demands. Purinergic signalling is known to be an important modulatory system in many parts of the CNS,
Witts, Emily Charlotte   +3 more
core   +1 more source

Methamphetamine reduces LTP and increases baseline synaptic transmission in the CA1 region of mouse hippocampus.

open access: yesPLoS ONE, 2010
Methamphetamine (METH) is an addictive psychostimulant whose societal impact is on the rise. Emerging evidence suggests that psychostimulants alter synaptic plasticity in the brain--which may partly account for their adverse effects.
Jarod Swant   +3 more
doaj   +1 more source

Determining the neurotransmitter concentration profile at active synapses [PDF]

open access: yes, 2009
Establishing the temporal and concentration profiles of neurotransmitters during synaptic release is an essential step towards understanding the basic properties of inter-neuronal communication in the central nervous system.
Beato, M.   +3 more
core   +1 more source

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