Results 31 to 40 of about 299,601 (285)

Male pheromones modulate synaptic transmission at the C. elegans neuromuscular junction in a sexually dimorphic manner

eLife, 2021
The development of functional synapses in the nervous system is important for animal physiology and behaviors, and its disturbance has been linked with many neurodevelopmental disorders.
Kang-Ying Qian, Wan-Xin Zeng, Yue Hao, Xian-Ting Zeng, Haowen Liu, Lei Li, Lili Chen, Fu-min Tian, Cindy Chang, Qi Hall, Chun-Xue Song, Shangbang Gao, Zhitao Hu, Joshua M Kaplan, Qian Li, Xia-Jing Tong   +15 more
doaj   +1 more source

mGluR-dependent synaptic plasticity in drug-seeking.

Frontiers in Pharmacology, 2012
A primary feature of drug addiction is the compulsive use despite negative consequences. A general consensus is emerging on the capacity of addictive substances to co-opt synaptic transmission and synaptic plasticity in brain circuits which are involved ...
Camilla eBellone, Manuel eMameli, Manuel eMameli, Manuel eMameli   +3 more
doaj   +1 more source

Tadr is an axonal histidine transporter required for visual neurotransmission in Drosophila

eLife, 2022
Neurotransmitters are generated by de novo synthesis and are essential for sustained, high-frequency synaptic transmission. Histamine, a monoamine neurotransmitter, is synthesized through decarboxylation of histidine by histidine decarboxylase (Hdc ...
Yongchao Han, Lei Peng, Tao Wang
doaj   +1 more source

Anti-allodynic and promotive effect on inhibitory synaptic transmission of riluzole in rat spinal dorsal horn

Biochemistry and Biophysics Reports, 2021
Riluzole (2-amino-6-(trifluoromethoxy)benzothiazole) is a drug known for its inhibitory effect on glutamatergic transmission and its anti-nociceptive and anti-allodynic effects in neuropathic pain rat models.
Ryo Taiji, Manabu Yamanaka, Wataru Taniguchi, Naoko Nishio, Shunji Tsutsui, Terumasa Nakatsuka, Hiroshi Yamada   +6 more
doaj   +1 more source

Thermal Impact on Spiking Properties in Hodgkin-Huxley Neuron with Synaptic Stimulus

, 2007
The effect of environmental temperature on neuronal spiking behaviors is investigated by numerically simulating the temperature dependence of spiking threshold of the Hodgkin-Huxley neuron subject to synaptic stimulus.
A. F. Huxley, A. L. Hodgkin, A. L. Hodgkin, A. L. Hodgkin, A. V. Holden, Aiyin Cao, F. Bezanilla, H. Xu, J. D. Miller, J. J. C. Rosenthal, J. S. Rothman, J. S. Schweitzer, J. W. Moore, Jiafu Wang, M. I. Rabinovich, M. Radmilovich, M. Volgushev, R. A. Sjodin, R. FitzHugh, R. FitzHugh, R. Guttman, R. Guttman, R. VanRullen, S. Kuang, Shenbing Kuang, Ting Zeng, V. Y. Vasilenko, X. Cao, Y. Zhao   +28 more
core   +2 more sources

Optimal interplay between synaptic strengths and network structure enhances activity fluctuations and information propagation in hierarchical modular networks

, 2020
In network models of spiking neurons, the joint impact of network structure and synaptic parameters on activity propagation is still an open problem. Here we use an information-theoretical approach to investigate activity propagation in spiking networks ...
Lima, Vinicius, Novato, João P., Pena, Rodrigo F. O., Roque, Antonio C., Shimoura, Renan O.   +4 more
core   +1 more source

Signal Propagation in Feedforward Neuronal Networks with Unreliable Synapses [PDF]

, 2011
In this paper, we systematically investigate both the synfire propagation and firing rate propagation in feedforward neuronal network coupled in an all-to-all fashion.
A Aertsen, A Kumar, A Kumar, AS Pikovsky, B Katz, B Katz, B Lindner, C Allen, C Li, C Rosenmund, CF Stevens, Chunguang Li, Daqing Guo, DK Smetters, DQ Guo, DR Chialvo, E Nordlie, EO Postma, H Câteau, J Friedrich, J Trommershäuser, J Trommershäuser, JJ Collins, JJ Collins, JJ Collins, K Hamaguchi, K Hamaguchi, KH Boven, M Abeles, M Diesmann, M Diesmann, M Raastad, MCW Rossum van, MO Gewaltig, MS Goldman, MS Goldman, N Masuda, N Masuda, P Dayan, PE Kloeden, PT Vogels, ST Wang, ST Wang, T Branco, T Shinozaki, T Shinozaki, T Tetzlaff, T Tetzlaff, U Hehl, W Maass, Y Aviel   +50 more
core   +1 more source

Diverse modes of synaptic signaling, regulation, and plasticity distinguish two classes of C. elegans glutamatergic neurons

eLife, 2017
Synaptic vesicle release properties vary between neuronal cell types, but in most cases the molecular basis of this heterogeneity is unknown. Here, we compare in vivo synaptic properties of two neuronal classes in the C.
Donovan Ventimiglia, Cornelia I Bargmann
doaj   +1 more source

Carbonic anhydrase inhibitor acetazolamide shifts synaptic vesicle recycling to a fast mode at the mouse neuromuscular junction [PDF]

, 2017
Acetazolamide (AZ), a molecule frequently used to treat different neurological syndromes, is an inhibitor of the carbonic anhydrase (CA), an enzyme that regulates pH inside and outside cells.
Bertone Cueto, Nicolás Iván, Cano, Raquel, Groisman, Ayelén Ivana, Mazzone, Graciela Luján, Tabares, Lucía, Uchitel, Osvaldo Daniel   +5 more
core   +1 more source

NPY-mediated synaptic plasticity in the extended amygdala prioritizes feeding during starvation

Nature Communications
Efficient control of feeding behavior requires the coordinated adjustment of complex motivational and affective neurocircuits. Neuropeptides from energy-sensing hypothalamic neurons are potent feeding modulators, but how these endogenous signals shape ...
Stephan Dodt, Noah V. Widdershooven, Marie-Luise Dreisow, Lisa Weiher, Lukas Steuernagel, F. Thomas Wunderlich, Jens C. Brüning, Henning Fenselau   +7 more
doaj   +1 more source