Results 101 to 110 of about 53,984 (298)
Synaptic actions of amyotrophic-lateral-sclerosis-associated G85R-SOD1 in the squid giant synapse [PDF]
, 2020 © The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Song, Y.
Song, Yuyu
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Regulation of synaptic vesicle fusion by protein kinase C
The Journal of Physiology, 1999 Activation of protein kinase C (PKC) by phorbol esters stimulates secretion of neurotransmitters from most presynaptic terminals. This action of PKC may be even more general, because secretion from many non-neuronal cells is also stimulated by these agents.
S, Hilfiker, G J, Augustine
openaire +3 more sources
Advanced Science, EarlyView.vEMINR is an ultra‐fast isotropic reconstruction method for vEM based on implicit neural representation, achieving over tenfold faster reconstruction and higher accuracy on 11 datasets, showing strong potential for large‐scale vEM data processing.
Jibin Yang +7 more
wiley +1 more source
eLife, 2016 Altered insulin signaling has been linked to widespread nervous system dysfunction including cognitive dysfunction, neuropathy and susceptibility to neurodegenerative disease.
Rebekah Elizabeth Mahoney +2 more
doaj +1 more source
Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium
Advanced Science, EarlyView.This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du +5 more
wiley +1 more source
Frontiers in Neuroscience, 2019 There is a general consensus that synaptic vesicular release by a full collapse process is the primary machinery of synaptic transmission. However, competing view suggests that synaptic vesicular release operates via a kiss-and-run mechanism.
Andreas W. Henkel +2 more
doaj +1 more source
Fast Snare Mediated Synaptic Vesicle Fusion in Supported Membranes
Biophysical Journal, 2013 In vitro reconstitution experiments have played an essential role in a large body of research on SNARE-mediated membrane fusion. One of the open questions is how well reconstituted membranes with recombinant proteins approximate the physiological membrane.Here we report experiments from a hybrid system consisting of purified synaptic vesicles from rat ...
Kiessling, V. +5 more
openaire +2 more sources
Advanced Science, EarlyView.Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong +12 more
wiley +1 more source
Membrane bridging by Munc13-1 is crucial for neurotransmitter release
eLife, 2019 Munc13-1 plays a crucial role in neurotransmitter release. We recently proposed that the C-terminal region encompassing the C1, C2B, MUN and C2C domains of Munc13-1 (C1C2BMUNC2C) bridges the synaptic vesicle and plasma membranes through interactions ...
Bradley Quade +9 more
doaj +1 more source
Sustained exocytosis after action potential-like stimulation at low frequencies in mouse chromaffin cells depends on a dynamin-dependent fast endocytotic process [PDF]
, 2016 Under basal conditions the action potential firing rate of adrenal chromaffin cells is lower than 0.5 Hz. The maintenance of the secretory response at such frequencies requires a continuous replenishment of releasable vesicles.
Alvarez, Yanina Daniela +7 more
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