Results 51 to 60 of about 29,089 (240)

DGKθ Catalytic Activity Is Required for Efficient Recycling of Presynaptic Vesicles at Excitatory Synapses

open access: yesCell Reports, 2016
Synaptic transmission relies on coordinated coupling of synaptic vesicle (SV) exocytosis and endocytosis. While much attention has focused on characterizing proteins involved in SV recycling, the roles of membrane lipids and their metabolism remain ...
Hana L. Goldschmidt   +5 more
doaj   +1 more source

Nanoscale Remodeling of Functional Synaptic Vesicle Pools in Hebbian Plasticity

open access: yesCell Reports, 2020
Summary: Vesicle pool properties are known determinants of synaptic efficacy, but their potential role as modifiable substrates in forms of Hebbian plasticity is still unclear.
Stephanie Rey   +3 more
doaj   +1 more source

Regulation of plasma membrane expansion during axon formation [PDF]

open access: yes, 2018
Here, will review current evidence regarding the signaling pathways and mechanisms underlying membrane addition at sites of active growth during axon formation.Fil: Quiroga, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas.
Bisbal, Mariano   +2 more
core   +1 more source

SNARE Regulatory Proteins in Synaptic Vesicle Fusion and Recycling

open access: yesFrontiers in Molecular Neuroscience, 2021
Membrane fusion is a universal feature of eukaryotic protein trafficking and is mediated by the soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) family.
Chad W. Sauvola   +2 more
doaj   +1 more source

Axonal amyloid precursor protein and its fragments undergo somatodendritic endocytosis and processing. [PDF]

open access: yes, 2015
Deposition of potentially neurotoxic Aβ fragments derived from amyloid precursor protein (APP) at synapses may be a key contributor to Alzheimer's disease.
Goldstein, Lawrence SB   +2 more
core   +1 more source

Mutations in human dynamin block an intermediate stage in coated vesicle formation [PDF]

open access: yes, 1993
The role of human dynamin in receptor-mediated endocytosis was investigated by transient expression of GTP-binding domain mutants in mammalian cells. Using assays which detect intermediates in coated vesicle formation, the dynamin mutants were found to ...
Damke, Hanna   +5 more
core   +3 more sources

Tyrosine phosphorylation of synaptophysin in synaptic vesicle recycling [PDF]

open access: yesBiochemical Society Transactions, 2005
The integral SV (synaptic vesicle) protein synaptophysin was one of the first nerve terminal proteins identified. However its role, if any, in the SV life cycle remains undetermined. One of the most prominent features of synaptophysin is that its cytoplasmic C-terminus largely consists of pentapeptide repeats initiated by a tyrosine residue ...
G J O, Evans, M A, Cousin
openaire   +2 more sources

Bio‐Inspired Molecular Events in Poly(Ionic Liquids)

open access: yesAdvanced Functional Materials, EarlyView.
Originating from dipolar and polar inter‐ and intra‐chain interactions of the building blocks, the topologies and morphologies of poly(ionic liquids) (PIL) govern their nano‐ and micro‐processibility. Modulating the interactions of cation‐anion pairs with aliphatic dipolar components enables the tunability of properties, facilitated by “bottom‐up ...
Jiahui Liu, Marek W. Urban
wiley   +1 more source

Sensing Exocytosis and Triggering Endocytosis at Synapses: Synaptic Vesicle Exocytosis–Endocytosis Coupling

open access: yesFrontiers in Cellular Neuroscience, 2018
The intact synaptic structure is critical for information processing in neural circuits. During synaptic transmission, rapid vesicle exocytosis increases the size of never terminals and endocytosis counteracts the increase. Accumulating evidence suggests
Xuelin Lou
doaj   +1 more source

Activity-dependent plasticity of transmitter release from nerve terminals in rat fast and slow muscles [PDF]

open access: yes, 2018
Available under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported license.Peer reviewedPublisher ...
Bewick, Guy Smith   +4 more
core   +1 more source

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