Results 91 to 100 of about 531,557 (374)

Rabconnectin3α Promotes Stable Activity of the H+ Pump on Synaptic Vesicles in Hair Cells

open access: yesJournal of Neuroscience, 2012
Acidification of synaptic vesicles relies on the vacuolar-type ATPase (V-ATPase) and provides the electrochemical driving force for neurotransmitter exchange.
Zev Einhorn   +3 more
semanticscholar   +1 more source

Synaptic vesicle structure [PDF]

open access: yesThe Journal of Cell Biology, 2006
![][1] A synaptic vesicle, up close and personal. TAKAMORI/ELSEVIER The first molecular level model of an organelle is described by Shigeo Takamori, Reinhard Jahn (Max-Planck Institute, Gottingen, Germany), and colleagues.
openaire   +2 more sources

Inertia of Synaptic Vesicle Exocytosis [PDF]

open access: yesBiophysical Journal, 2010
Reliable synaptic vesicle exocytosis in primary hippocampal neurons depends on the number and availability of release-competent vesicles, their recharging with neurotransmitters and the kinetics of exo- endocytosis. We have analyzed the correlations between several exocytotic kinetic parameters by measuring FM-styryl dyes (FM 1-43, FM 4-64 and FM 5-95)
Armin Stroebel   +6 more
openaire   +2 more sources

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Determining the neurotransmitter concentration profile at active synapses [PDF]

open access: yes, 2009
Establishing the temporal and concentration profiles of neurotransmitters during synaptic release is an essential step towards understanding the basic properties of inter-neuronal communication in the central nervous system.
A Barberis   +144 more
core   +2 more sources

Storage and Uptake of d-Serine into Astrocytic Synaptic-Like Vesicles Specify Gliotransmission

open access: yesJournal of Neuroscience, 2013
Glial cells are increasingly recognized as active players that profoundly influence neuronal synaptic transmission by specialized signaling pathways. In particular, astrocytes have been shown recently to release small molecules, such as the amino acids l-
M. Martineau   +9 more
semanticscholar   +1 more source

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao   +5 more
wiley   +1 more source

Synaptic Ribbons Require Ribeye for Electron Density, Proper Synaptic Localization, and Recruitment of Calcium Channels

open access: yesCell Reports, 2016
Synaptic ribbons are structures made largely of the protein Ribeye that hold synaptic vesicles near release sites in non-spiking cells in some sensory systems.
Caixia Lv   +8 more
doaj   +1 more source

Research progress on the role of type I vesicular glutamate transporter (VGLUT1) in nervous system diseases

open access: yesCell & Bioscience, 2020
Glutamate (Glu) is the predominant excitatory neurotransmitter in the central nervous system (CNS). Glutamatergic transmission is critical for controlling neuronal activity.
Xianchao Du   +8 more
doaj   +1 more source

ADAR-mediated RNA editing suppresses sleep by acting as a brake on glutamatergic synaptic plasticity. [PDF]

open access: yes, 2016
It has been postulated that synaptic potentiation during waking is offset by a homoeostatic reduction in net synaptic strength during sleep. However, molecular mechanisms to support such a process are lacking. Here we demonstrate that deficiencies in the
Dickman, DK   +3 more
core  

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