Results 11 to 20 of about 65,541 (146)
Synaptic vesicle endocytosis [PDF]
Current Opinion in Neurobiology, 1997 Exocytosis of synaptic vesicles is followed rapidly by reinternalization and recycling of their membranes. Recent studies have confirmed the key role of clathrin-mediated endocytosis in synaptic vesicle reformation and have identified new proteins that participate in this process.
CREMONA , OTTAVIO, DE CAMILLI P.
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Synaptic Vesicle Exocytosis [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 Presynaptic nerve terminals release neurotransmitters by synaptic vesicle exocytosis. Membrane fusion mediating synaptic exocytosis and other intracellular membrane traffic is affected by a universal machinery that includes SNARE (for "soluble NSF-attachment protein receptor") and SM (for "Sec1/Munc18-like") proteins.
Thomas C, Südhof, Josep, Rizo
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Synaptic Vesicle Endocytosis [PDF]
Cold Spring Harbor Perspectives in Biology, 2012 Neurons can sustain high rates of synaptic transmission without exhausting their supply of synaptic vesicles. This property relies on a highly efficient local endocytic recycling of synaptic vesicle membranes, which can be reused for hundreds, possibly thousands, of exo-endocytic cycles. Morphological, physiological, molecular, and genetic studies over
Yasunori, Saheki, Pietro, De Camilli
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Nature Structural & Molecular Biology, 2008 The core of the neurotransmitter release machinery is formed by SNARE complexes, which bring the vesicle and plasma membranes together and are key for fusion, and by Munc18-1, which controls SNARE-complex formation and may also have a direct role in fusion.
Josep, Rizo, Christian, Rosenmund
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Trans-synaptic assemblies link synaptic vesicles and neuroreceptors [PDF]
Science Advances, 2021 Tripartite trans-synaptic assemblies directly link pre- and postsynaptic complexes crucial for synaptic transmission.
Antonio Martinez-Sanchez +6 more
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Communications Biology, 2021 Yasunori Mori et al. find that a subset of neurotransmitter-bearing synaptic vesicles are marked for release by the endosomal Q-SNARE protein Stx7. They show that Stx7 function is necessary for the rapid replenishment of synaptic vesicles that is needed ...
Yasunori Mori +3 more
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Rabconnectin-3α/DMXL2 Is Locally Enriched at the Synaptic Ribbon of Rod Photoreceptor Synapses
Cells, 2023 Ribbon synapses reliably transmit synaptic signals over a broad signalling range. Rod photoreceptor ribbon synapses are capable of transmitting signals generated by the absorption of single photons.
Alina Dittrich +3 more
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Frontiers in Synaptic Neuroscience, 2018 Cortical computations rely on functionally diverse and highly dynamic synapses. How their structural composition affects synaptic transmission and plasticity and whether they support functional diversity remains rather unclear.
Astrid Rollenhagen +7 more
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Frontiers in Neuroanatomy, 2015 The spatial interactions of synaptic vesicles in synapses were assessed after a detailed characterization of size, shape, and orientation of the synaptic vesicles.
Mahdieh eKhanmohammadi +2 more
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Localization and mobility of synaptic vesicles in Myosin VI mutants of Drosophila. [PDF]
PLoS ONE, 2014 BACKGROUND: At the Drosophila neuromuscular junction (NMJ), synaptic vesicles are mobile; however, the mechanisms that regulate vesicle traffic at the nerve terminal are not fully understood.
Marta Kisiel +2 more
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