Results 21 to 30 of about 549,591 (370)
iScience, 2021 Summary: Although defective synaptic transmission was suggested to play a role in neurodegenerative diseases, the dynamics and vesicle pools of synaptic vesicles during neurodegeneration remain elusive.
Sidong Chen +7 more
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Synaptic Vesicle Endocytosis [PDF]
Cold Spring Harbor Perspectives in Biology, 2012 Neurons can sustain high rates of synaptic transmission without exhausting their supply of synaptic vesicles. This property relies on a highly efficient local endocytic recycling of synaptic vesicle membranes, which can be reused for hundreds, possibly thousands, of exo-endocytic cycles. Morphological, physiological, molecular, and genetic studies over
Yasunori, Saheki, Pietro, De Camilli
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Synaptic actions of amyotrophic-lateral-sclerosis-associated G85R-SOD1 in the squid giant synapse [PDF]
, 2020 © The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Song, Y.
Song, Yuyu
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MethodsX, 2021 Two types of secretory vesicles co-exist at some presynaptic terminals. Clear synaptic vesicles (CSV) release their contents at the synaptic active zone, upon single impulses, while dense-core vesicles (DCV) usually release their contents in the ...
Citlali Trueta
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Nature Structural & Molecular Biology, 2008 The core of the neurotransmitter release machinery is formed by SNARE complexes, which bring the vesicle and plasma membranes together and are key for fusion, and by Munc18-1, which controls SNARE-complex formation and may also have a direct role in fusion.
Josep, Rizo, Christian, Rosenmund
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Reduced expression of the vesicular acetylcholine transporter and neurotransmitter content affects synaptic vesicle distribution and shape in mouse neuromuscular junction. [PDF]
PLoS ONE, 2013 In vertebrates, nerve muscle communication is mediated by the release of the neurotransmitter acetylcholine packed inside synaptic vesicles by a specific vesicular acetylcholine transporter (VAChT).
Hermann A Rodrigues +8 more
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Activity-dependence of synaptic vesicle dynamics [PDF]
, 2017 The proper function of synapses relies on efficient recycling of synaptic vesicles. The small size of synaptic boutons has hampered efforts to define the dynamical states of vesicles during recycling.
Forte, Luca A +2 more
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Trans-synaptic assemblies link synaptic vesicles and neuroreceptors [PDF]
Science Advances, 2021 Tripartite trans-synaptic assemblies directly link pre- and postsynaptic complexes crucial for synaptic transmission.
Antonio Martinez-Sanchez +6 more
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F1000Research, 2017 Synaptic vesicle recycling is essential for sustained and reliable neurotransmission. A key component of synaptic vesicle recycling is the synaptic vesicle biogenesis process that is observed in synapses and that maintains the molecular identity of ...
Natali L. Chanaday, Ege T. Kavalali
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Communications Biology, 2021 Yasunori Mori et al. find that a subset of neurotransmitter-bearing synaptic vesicles are marked for release by the endosomal Q-SNARE protein Stx7. They show that Stx7 function is necessary for the rapid replenishment of synaptic vesicles that is needed ...
Yasunori Mori +3 more
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