Results 11 to 20 of about 354,036 (296)
Synaptic Vesicles Dynamics in Neocortical Epilepsy [PDF]
Frontiers in Cellular Neuroscience, 2020 Neuronal hyperexcitability often results from an unbalance between excitatory and inhibitory neurotransmission, but the synaptic alterations leading to enhanced seizure propensity are only partly understood.
Eleonora Vannini +8 more
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Mover is a homomeric phospho-protein present on synaptic vesicles. [PDF]
PLoS ONE, 2013 With remarkably few exceptions, the molecules mediating synaptic vesicle exocytosis at active zones are structurally and functionally conserved between vertebrates and invertebrates. Mover was found in a yeast-2-hybrid assay using the vertebrate-specific
Saheeb Ahmed +9 more
doaj +2 more sources
Synaptic Vesicles in the Fast Lane [PDF]
Science, 2004 It is well established that a subset of synaptic vesicles seem to be preferentially recycled after neurotransmitter release. It has been assumed that these vesicles must cluster at the active zones of the presynaptic nerve terminal membrane so that they can rapidly release their contents in response to electrical stimulation.
Holt, Matthew, Jahn, Reinhard
openaire +5 more sources
RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System. [PDF]
Adv Sci (Weinh)Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Rankovic B +21 more
europepmc +2 more sources
Frontiers in Cell and Developmental Biology, 2023 Presynapses locally recycle synaptic vesicles to efficiently communicate information. During use and recycling, proteins on the surface of synaptic vesicles break down and become less efficient.
Mason Parkes +2 more
doaj +1 more source
MethodsX, 2021 Two types of secretory vesicles co-exist at some presynaptic terminals. Clear synaptic vesicles (CSV) release their contents at the synaptic active zone, upon single impulses, while dense-core vesicles (DCV) usually release their contents in the ...
Citlali Trueta
doaj +1 more source
Reduced expression of the vesicular acetylcholine transporter and neurotransmitter content affects synaptic vesicle distribution and shape in mouse neuromuscular junction. [PDF]
PLoS ONE, 2013 In vertebrates, nerve muscle communication is mediated by the release of the neurotransmitter acetylcholine packed inside synaptic vesicles by a specific vesicular acetylcholine transporter (VAChT).
Hermann A Rodrigues +8 more
doaj +1 more source
Synaptic Vesicle Exocytosis [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 Presynaptic nerve terminals release neurotransmitters by synaptic vesicle exocytosis. Membrane fusion mediating synaptic exocytosis and other intracellular membrane traffic is affected by a universal machinery that includes SNARE (for "soluble NSF-attachment protein receptor") and SM (for "Sec1/Munc18-like") proteins.
Thomas C, Südhof, Josep, Rizo
openaire +2 more sources
Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]
, 1994 Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
MANFRED GRATZL, Gratzl, Manfred
core +1 more source
Effects of synaptic vesicles on actin polymerization [PDF]
, 1996 We have analyzed the effects of synaptic vesicles on actin polymerization by using a time-resolved spectrofluorometric assay. We have found that synaptic vesicles have complex effects on the kinetics of actin polymerization, which vary depending on ...
P. E. Ceccaldi +10 more
core +2 more sources