Results 51 to 60 of about 531,557 (374)
Clathrin regenerates synaptic vesicles from endosomes
Nature, 2014 Ultrafast endocytosis can retrieve a single, large endocytic vesicle as fast as 50–100 ms after synaptic vesicle fusion. However, the fate of the large endocytic vesicles is not known.
Shigeki Watanabe +9 more
semanticscholar +1 more source
Binding of Rab3A to Synaptic Vesicles [PDF]
Journal of Biological Chemistry, 2000 Prenylated Rab GTPases cycle between membrane-bound and soluble forms. Membrane-bound GDP-Rabs interact with GDP dissociation inhibitor (GDI), resulting in the dissociation of a Rab.GDI complex, which in turn serves as a precursor for the membrane re-association of Rabs. We have now characterized the binding of Rab3A to synaptic vesicles in vitro using
Chou, J., Jahn, R.
openaire +4 more sources
Mover is a homomeric phospho-protein present on synaptic vesicles.
PLoS ONE, 2013 With remarkably few exceptions, the molecules mediating synaptic vesicle exocytosis at active zones are structurally and functionally conserved between vertebrates and invertebrates. Mover was found in a yeast-2-hybrid assay using the vertebrate-specific
Saheeb Ahmed +9 more
doaj +1 more source
Depolarization Redistributes Synaptic Membrane and Creates a Gradient of Vesicles on the Synaptic Body at a Ribbon Synapse [PDF]
, 2002 We used electron tomography of frog saccular hair cells to reconstruct presynaptic ultrastructure at synapses specialized for sustained transmitter release.
Crum, John +3 more
core +1 more source
Current Biology, 1999 Thomas Sudhof, Pietro De Camilli, Reinhard Jahn and Richard Scheller, to name but a few. Although the competitive, fast-paced nature of the field means you're unlikely to find them all in the same room at the same time.
openaire +3 more sources
Synaptic Transmission: Kinetics of synaptic-vesicle recycling [PDF]
Current Biology, 1995 The kinetics of different steps in synaptic-vesicle recycling, including exocytosis, internalization and repriming, have recently been estimated in various types of living cell.
William J. Betz, Ling-Gang Wu
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Incomplete vesicular docking limits synaptic strength under high release probability conditions
eLife, 2020 Central mammalian synapses release synaptic vesicles in dedicated structures called docking/release sites. It has been assumed that when voltage-dependent calcium entry is sufficiently large, synaptic output attains a maximum value of one synaptic ...
Gerardo Malagon +4 more
doaj +1 more source
Recycling of Synaptic Vesicles
, 1997 Publisher Summary A widely accepted model describes the synaptic vesicle cycle as a modification of the receptor-mediated recycling pathway present in all cells. This pathway, by which cell surface receptors, like transferrin or low-density lipoprotein receptors, are internalized and recycled back to the surface, involves two distinct vesicular ...
Vladimir I. Slepnev +7 more
openaire +3 more sources
Cholesterol and synaptic vesicle exocytosis [PDF]
Communicative & Integrative Biology, 2010 LIPIDS MAY AFFECT SYNAPTIC FUNCTION IN AT LEAST TWO WAYS: by acting as ligands for effector proteins [e.g., phosphatidylinositol (4,5) bisphosphate, diacylglycerol-mediated signaling] or by modifying the physicochemical properties and molecular organization of synaptic membranes.
Rosa P, Fratangeli A
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HDAC6 is a bruchpilot deacetylase that facilitates neurotransmitter release [PDF]
, 2014 Presynaptic densities are specialized structures involved in synaptic vesicle tethering and neurotransmission; however, the mechanisms regulating their function remain understudied.
Dermaut, Bart +8 more
core +3 more sources