Results 51 to 60 of about 65,541 (146)
Cell Reports, 2016 Synaptic ribbons are structures made largely of the protein Ribeye that hold synaptic vesicles near release sites in non-spiking cells in some sensory systems.
Caixia Lv +8 more
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Regulation of synaptic vesicle docking by different classes of macromolecules in active zone material. [PDF]
PLoS ONE, 2012 The docking of synaptic vesicles at active zones on the presynaptic plasma membrane of axon terminals is essential for their fusion with the membrane and exocytosis of their neurotransmitter to mediate synaptic impulse transmission.
Joseph A Szule +5 more
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Synaptic Vesicle Dynamics sans Dynamin [PDF]
Neuron, 2007 The neuron-specific guanosine triphosphatase dynamin 1 has been hypothesized to be critically required for pinching off synaptic vesicles during endocytosis. In a recent publication in Science, Ferguson et al. describe a series of experiments demonstrating an unexpectedly selective requirement of dynamin 1 in synaptic vesicle endocytosis only during ...
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Recycling of Synaptic Vesicles
, 1997 Publisher Summary A widely accepted model describes the synaptic vesicle cycle as a modification of the receptor-mediated recycling pathway present in all cells. This pathway, by which cell surface receptors, like transferrin or low-density lipoprotein receptors, are internalized and recycled back to the surface, involves two distinct vesicular ...
R, Bauerfeind +7 more
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Synaptic vesicle proteins and active zone plasticity
Frontiers in Synaptic Neuroscience, 2016 Neurotransmitter is released from synaptic vesicles at the highly specialized presynaptic active zone. The complex molecular architecture of active zones mediates the speed, precision and plasticity of synaptic transmission.
Robert J Kittel, Manfred eHeckmann
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Journal of Extracellular VesiclesC1q is released by microglia, localizes on weak synapses and acts as a tag for microglial synaptic pruning. However, how C1q tags synapses during the pruning period remains to be fully elucidated.
Giulia D'Arrigo +18 more
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Munc13-1 and Munc18-1 together prevent NSF-dependent de-priming of synaptic vesicles
Nature Communications, 2017 The molecular mechanism underlying the generation and maintenance of the readily releasable pool composed of primed synaptic vesicles is only partially known.
Enqi He +6 more
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Clarinet (CLA-1), a novel active zone protein required for synaptic vesicle clustering and release
eLife, 2017 Active zone proteins cluster synaptic vesicles at presynaptic terminals and coordinate their release. In forward genetic screens, we isolated a novel Caenorhabditis elegans active zone gene, clarinet (cla-1).
Zhao Xuan +6 more
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Frontiers in Neuroanatomy, 2018 Active zone material is an organelle that is common to active zones along the presynaptic membrane of chemical synapses. Electron tomography on active zones at frog neuromuscular junctions has provided evidence that active zone material directs the ...
Jae H. Jung +8 more
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