Results 121 to 130 of about 4,005 (212)

Evolutionary genomics of plant genes encoding N-terminal-TM-C2 domain proteins and the similar FAM62 genes and synaptotagmin genes of metazoans

open access: yesBMC Genomics, 2007
Background Synaptotagmin genes are found in animal genomes and are known to function in the nervous system. Genes with a similar domain architecture as well as sequence similarity to synaptotagmin C2 domains have also been found in plant genomes.
Craxton Molly
doaj   +1 more source

Dissecting the functions of Synaptotagmin-1 and Synaptotagmin-7 in synaptic transmission

open access: yes, 2023
Die zugrundeliegenden Mechanismen, die die neuronale Kommunikation durch synaptische Übertragung steuern, werden seit Jahrzehnten in zahlreichen Studien untersucht. Die Neurotransmission erfolgt im präsynaptischen Bouton, in dem sich spezialisierte sekretorische Organellen, die synaptischen Vesikel (SVs), befinden.
openaire   +2 more sources

In vitro fusion of single synaptic and dense core vesicles reproduces key physiological properties.

open access: yes, 2019
Regulated exocytosis of synaptic vesicles is substantially faster than of endocrine dense core vesicles despite similar molecular machineries. The reasons for this difference are unknown and could be due to different regulatory proteins, different ...
Castle, J.   +10 more
core   +1 more source

Reduced synaptic vesicle protein 2A in extracellular vesicles and brains of Alzheimer’s disease: associations with Aβ, tau, synaptic proteins and APOE ε4

open access: yesTranslational Neurodegeneration
Background Alzheimer’s disease (AD) is characterized by accumulation of amyloid-β (Aβ) plaques, tau neurofibrillary Tangles and synaptic dysfunction.
Jana Nussbaumer   +14 more
doaj   +1 more source

LY 294002 inhibits adenosine receptor activation by a mechanism independent of effects on PI-3 kinase or casein kinase II [PDF]

open access: yes, 2005
T. J. Searl   +20 more
core   +1 more source

Increased expression of SNARE proteins and synaptotagmin IV in islets from pregnant rats and in vitro prolactin-treated neonatal islets

open access: yesBiological Research, 2006
During pregnancy and the perinatal period of life, prolactin (PRL) and other lactogenic substances induce adaptation and maturation of the stimulus-secretion coupling system in pancreatic β-cells. Since the SNARE molecules, SNAP-25, syntaxin 1, VAMP-
DANIEL A CUNHA   +5 more
doaj  

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