CD138 (syndecan-1) expression in health and disease.
Histology and histopathology, 2014 CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions. In adult human tissues, CD138 is predominantly expressed in epithelial cells and plasmacytes.
Palaiologou, Marina +2 more
openaire +4 more sources
The expression of syndecan-1 in psoriatic epidermis [PDF]
Archives of Dermatological Research, 2008 Psoriasis is a chronic inflammatory skin disease characterized by exaggerated keratinocyte proliferation. Current opinion indicates that psoriasis is driven by T cell-mediated immune responses targeting keratinocytes. However, psoriasis cannot be explained solely on the basis of T-cell activation, and it is likely that an intrinsic alteration in ...
Tomas, Davor +3 more
openaire +5 more sources
Syndecan-1 (CD138) Immunoreactivity in Bone Marrow Biopsies of Multiple Myeloma: Shed Syndecan-1 Accumulates in Fibrotic Regions [PDF]
Modern Pathology, 2001 Syndecan-1 (CD138) mediates myeloma cell adhesion, and loss of syndecan-1 from the cell surface may contribute to myeloma proliferation and dissemination. Flow cytometry analysis of myeloma cells in bone marrow specimens shows heterogeneity in cell surface syndecan-1 expression.
I B, Bayer-Garner +4 more
openaire +2 more sources
Differences in E-Cadherin and Syndecan-1 Expression in Different Types of Ameloblastomas
Analytical Cellular Pathology, 2018 Ameloblastomas are a group of benign, locally aggressive, recurrent tumors characterized by their slow and infiltrative growth. E-Cadherin and syndecan-1 are cell adhesion molecules related to the behavior of various tumors, including ameloblastomas ...
Ramón G. Carreón-Burciaga +5 more
doaj +1 more source
Gene expression patterns following unilateral traumatic brain injury reveals a local pro-inflammatory and remote anti-inflammatory response. [PDF]
, 2013 BackgroundTraumatic brain injury (TBI) results in irreversible damage at the site of impact and initiates cellular and molecular processes that lead to secondary neural injury in the surrounding tissue.
Ford, Byron D +5 more
core +2 more sources
TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent [PDF]
, 2008 Toll-like receptor (TLR) signaling induces a rapid reorganization of the actin cytoskeleton in cultured mouse dendritic cells (DC), leading to enhanced antigen endocytosis and a concomitant loss of filamentous actin–rich podosomes.
Chan, Kui Ming +6 more
core +5 more sources
Association of Syndecan-1 immunoexpression with epithelial dysplasia in oral verrucous carcinoma
Bangabandhu Sheikh Mujib Medical University JournalBackground: Oral verrucous carcinoma (OVC) is an uncommon variant of well-differentiated squamous cell carcinoma with an excellent prognosis. Epithelial dysplasia in OVC is a sign of a poorer prognosis.
Md. Akhtaruzzaman +4 more
doaj +1 more source
Peripheral desmoplastic ameloblastoma : histopathological and immunohistochemical profile of a case [PDF]
, 2010 In this study we present a rare case of peripheral desmoplastic ameloblastoma and discuss its clinical features, histopathology, and inmunoshistochemical profile.
Almeida, Oslei Paes de +4 more
core +1 more source
Immunohistochemical analysis of syndecan-1 in leukoplakia and oral submucous fibrosis
Dental Research Journal, 2013 Background: Syndecan-1 is abundant in normal tissues and reduced in squamous cell carcinomas. Leukoplakia and oral submucous fibrosis (OSF) are oral pre-cancerous disorders that have potential for malignant transformation.
Sushant S Kamat, G S Kumar, Ajit V Koshy
doaj +1 more source
Scientific Reports, 2021 Fetal growth restriction is a leading cause of stillbirth that often remains undetected during pregnancy. Identifying novel biomarkers may improve detection of pregnancies at risk.
Damanpreet Garcha +26 more
doaj +1 more source