Results 11 to 20 of about 107,687,715 (215)
Syndecan-1 (CD138), Carcinomas and EMT [PDF]
International Journal of Molecular Sciences, 2021 Cell surface proteoglycans are known to be important regulators of many aspects of cell behavior. The principal family of transmembrane proteoglycans is the syndecans, of which there are four in mammals. Syndecan-1 is mostly restricted to epithelia, and bears heparan sulfate chains that are capable of interacting with a large array of polypeptides ...
Couchman, John R., John R. Couchman
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Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on SDC1 (syndecan 1), with data on DNA, on the protein encoded, and where the gene is implicated.
Purushothaman, A, Sanderson, RD
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Heparanase regulates levels of syndecan-1 in the nucleus.
PLoS ONE, 2009 Syndecan-1 is a transmembrane heparan sulfate-bearing proteoglycan known to regulate multiple biological functions at the cell surface and within the extracellular matrix.
Ligong Chen, Ralph D Sanderson
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Syndecan expressions in the human amnion and chorionic plate [PDF]
European Journal of Histochemistry, 2010 The syndecan family consists of four distinct membrane glycoproteins in mammals. Syndecans control cell proliferation, differentiation, adhesion and migration through participation in cell-cell interactions, anchorage of cells to the extracellular ...
T. Lorenzi +7 more
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Syndecan-1 insights in mesothelioma
, 2017 Syndecan-1 is a cell surface heparan sulfate proteoglycan expressing on epithelial cells. Heparan sulfate (HS) chains on syndecan-1 constitute growth factor attachment sites and facilitate growth factors to bind their respective receptors. This binding property of HS chains allows syndecan-1 to be involved in various cellular processes.
Ghazal Heidari Hamedani (18667603)
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Frontiers in Cardiovascular Medicine, 2021 Background: Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host responses to infection. Recent studies have suggested that endotheliopathy may be the common basis for multiple organ failure in sepsis.
Kosaku Hatanaka +7 more
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Syndecan-1 (CD138) modulates triple-negative breast cancer stem cell properties via regulation of LRP-6 and IL-6-mediated STAT3 signaling. [PDF]
PLoS ONE, 2013 Syndecan-1 (CD138), a heparan sulfate proteoglycan, acts as a coreceptor for growth factors and chemokines and is a molecular marker associated with epithelial-mesenchymal transition during development and carcinogenesis.
Sherif A Ibrahim +12 more
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Focus on Molecules: Syndecan-1 [PDF]
Experimental Eye Research, 2011 Syndecan-1 (NP_001006947.1) is a widely expressed cell surface heparan sulfate proteoglycan whose molecular cloning as ‘syndecan’ (Saunders et al, ’89), later known as syndecan-1, was the springboard for the discovery of syndecans-2 through -4. Expression in the eye has been documented in corneal, limbal (GDS2433) and conjunctival epithelial cells ...
Yinghui, Zhang +4 more
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Syndecan-1 in Liver Diseases [PDF]
Pathology & Oncology Research, 2019 Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver.
Regős E +6 more
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Syndecan-1 in vascular mechanosensing [PDF]
, 2021 The cells of vascular tissues are subject to biophysical and biochemical cues from their microenvironment. These cues are relayed to cells via adhesion receptors on the cell surface to components of the extracellular matrix, cytoskeleton-linked proteins ...
Le, Victoria Phuong
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