Results 41 to 50 of about 107,687,715 (215)
The Role of Syndecan-1 in Malignancies
Annals of Medicine, 1996 Syndecans form a family of cell surface proteoglycans, which can interact with various effector molecules, such as extracellular matrix (ECM) molecules and growth factors. Syndecan-1 is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic ...
P, Inki, M, Jalkanen
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Distribution of syndecan-1 protein in developing mouse teeth
Frontiers in Physiology, 2015 Syndecan-1 is a cell surface proteoglycan involved in the regulation of various biological processes such as proliferation, migration, condensation and differentiation of cells, intercellular communication and morphogenesis.
Anna eFilatova +2 more
doaj +1 more source
Molecular targets and signaling pathways regulated by nuclear translocation of syndecan-1
BMC Cell Biology, 2017 Background The cell-surface heparan sulfate proteoglycan syndecan-1 is important for tumor cell proliferation, migration, and cell cycle regulation in a broad spectrum of malignancies.
Tünde Szatmári +6 more
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Syndecan-1 as a predictor of vulnerable atherosclerotic plaques. [PDF]
Front Cell Dev BiolAimsCardiovascular disease remains a major global health concern, with atherosclerosis (AS) being a significant contributor. Vulnerable plaques play a critical role in acute cardiovascular events. Syndecan-1 (SDC-1), a vital membrane proteoglycan in the vascular endothelial glycocalyx, is believed to be associated with plaque progression.
Qiu Y +5 more
europepmc +4 more sources
Effects of overexpression of syndecan-1 in mesenchymal tumor cells
, 2011 BackgroundAll cells carry a transmembrane proteoglycan calledsyndecan. Syndecans influence many functions like cell migration, cell adhesionand cell proliferation and it is involved in cellular signaling andtumourigenesis.
Grönkvist, Pamela
core +4 more sources
Endothelial glycocalyx during early reperfusion in patients undergoing cardiac surgery.
PLoS ONE, 2021 BackgroundExperimental cardiac ischemia-reperfusion injury causes degradation of the glycocalyx and coronary washout of its components syndecan-1 and heparan sulfate.
Arie Passov +5 more
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Plasma concentrations of syndecan‐1 are dependent on kidney function [PDF]
Acta Anaesthesiologica Scandinavica, 2021 AbstractBackgroundElevated plasma concentrations of syndecan‐1 and heparan sulfate in studies of trauma, sepsis, and major surgery are commonly assumed to indicate acute glycocalyx degradation. We explored a possible role of the kidneys for these elevations.MethodsPlasma and urine concentrations of syndecan‐1, heparan sulfate, and biomarkers of ...
Robert G. Hahn +2 more
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The Nature of Cell‐Penetrating Poly(disulfide)s
Angewandte Chemie, EarlyView.The mode of action of cell‐penetrating poly(disulfide)s (CPDs) is elucidated to understand thiol‐mediated uptake (TMU) in general and guide future efforts to control cellular entry for chemicals delivery and pathogen defense. ABSTRACT Cell‐penetrating poly(disulfide)s (CPDs) are the most popular thiol‐mediated uptake (TMU) tools for delivering attached
Saidbakhrom Saidjalolov +7 more
wiley +2 more sources
Molecular Medicine, 2021 Background We investigated the feasibility of two biomarkers of endothelial damage (Syndecan-1 and thrombomodulin) in coronavirus disease 2019 (COVID-19), and their association with inflammation, coagulopathy, and mortality.
Dong Zhang +11 more
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Journal of Bone Oncology, 2014 Background: Breast cancer often metastasizes into bone and leads to osteolytic lesions. The underlying mechanisms, however, are complex and not fully understood.
Peggy Benad-Mehner +5 more
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