Results 31 to 40 of about 107,687,715 (215)
Aberrant Expression of Syndecan-1 in Cervical Cancers [PDF]
Pathology & Oncology Research, 2020 Syndecan-1, is a transmembrane heparan/chondroitin sulfate proteoglycan necessary for cell-cell and cell-matrix interactions. Its decreased level on the cell surface correlates with poor prognosis in several tumor types. Aberrant stromal localization of syndecan-1 is also considered an unfavorable prognostic factor in various human malignancies. In the
Katalin Karászi +7 more
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Comparison of syndecan levels.
, 2022 A comparison of syndecan expression as measured by real-time PCR demonstrating that there is no difference in A) syndecan-1, B) syndecan-2, C) syndecan-3, and 4) syndecan-4 expression when H1N1 infected human umbilical vein endothelial cells are compared
Olan Jackson-Weaver (11512962) +9 more
core +1 more source
PLoS ONE, 2009 Syndecan-1 forms complexes with growth factors and their cognate receptors in the cell membrane. We have previously reported a tubulin-mediated translocation of syndecan-1 to the nucleus.
Fang Zong +9 more
doaj +1 more source
Alternative signaling pathways triggered by different mechanisms of serpin endocytosis [PDF]
, 2006 Protease Nexin-1 (PN-1), a 43 KDa glycoprotein, is known as a serpin (serine protease inhibitor) regulating extracellular proteolytic activity. It strongly inhibits the activity of several serine proteases such as thrombin, tissue plasminogen activator ...
Li, Xiaobiao
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Inhibition by the Soluble Syndecan-1 Ectodomains Delays Wound Repair in Mice Overexpressing Syndecan-1 [PDF]
Journal of Biological Chemistry, 2004 Wound repair is a tightly regulated process stimulated by proteases, growth factors, and chemokines, which are modulated by heparan sulfate. To characterize further the role of the heparan sulfate proteoglycan syndecan-1 in wound repair, we generated mice overexpressing syndecan-1 (Snd/Snd) and studied dermal wound repair.
Varpu, Elenius +4 more
openaire +2 more sources
Frontiers in Oncology, 2013 Proteoglycans and in particular the syndecans are involved in the differentiation process across the epithelial-mesenchymal axis, principally through their ability to bind growth factors and modulate their downstream signalling.
Tünde eSzatmári, Katalin eDobra
doaj +1 more source
Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation. [PDF]
PLoS ONE, 2014 BACKGROUND: The heparan sulfate proteoglycan syndecan-1 (CD138) was shown to regulate inflammatory responses by binding chemokines and cytokines and interacting with adhesion molecules, thereby modulating leukocyte trafficking to tissues.
Paulina M Kowalewska +2 more
doaj +1 more source
Syndecan-1: A Quantitative Marker for the Endotheliopathy of Trauma [PDF]
Journal of the American College of Surgeons, 2017 BACKGROUND: Endothelial glycocalyx breakdown elicits syndecan-1 shedding and endotheliopathy of trauma (EoT). We hypothesized that a cutoff syndecan-1 level can identify patients with endothelial dysfunction who would have poorer outcomes.
Gonzalez Rodriguez, Erika +10 more
openaire +3 more sources
Die Bedeutung der Proteoglykane Syndecan-1 und Syndecan-4 während der Frakturheilung [PDF]
, 2013 Die Frakturheilung stellt einen hochkomplexen Reparaturmechanismus dar, der Prozesse der Embryogenese im entzuendlichen Kontext rekapituliert. Die beiden Heparansulfat-Proteoglykane (HSPG) Syndecan-1 und Syndecan-4 sind an zahlreichen Heilungs- und ...
Hidding, H. (Heriburg)
core +3 more sources
Detection of Syndecan-1 and Heparanase-1 Genes in Esophageal Carcinoma by Quantitative RT-PCR
Cancer Biology & Medicine, 2010 OBJECTIVE To quantitatively explore the expression of Syndecan-1 and heparanase-1 in esophageal cancer tissue as well as their relationship with the clinicopathological factors, in order to evaluate their roles in tumor invasion and metastasis.METHODS
Jun-li SI, Yu-qin QI, Jing-yuan CUI
doaj +1 more source