Results 31 to 40 of about 11,302 (215)
Biomarker profiles of acute heart failure patients with a mid-range ejection fraction [PDF]
, 2017 OBJECTIVES: In this study, the authors used biomarker profiles to characterize differences between patients with acute heart failure with a midrange ejection fraction (HFmrEF) and compare them with patients with a reduced (heart failure with a ...
Bloomfield, Daniel M +16 more
core +2 more sources
Syndecan-2 is a novel target of insulin-like growth factor binding protein-3 and is over-expressed in fibrosis [PDF]
, 2012 Extracellular matrix deposition and tissue scarring characterize the process of fibrosis. Transforming growth factor beta (TGFβ) and Insulin-like growth factor binding protein-3 (IGFBP-3) have been implicated in the pathogenesis of fibrosis in various ...
Adriana T. Larregina +7 more
core +4 more sources
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Antirheumatic treatment is associated with reduced serum Syndecan-1 in Rheumatoid Arthritis.
PLoS ONE, 2021 The endothelial glycocalyx (EG) is essential for proper function of the endothelium and for vascular integrity, but its role in premature atherogenesis in rheumatoid arthritis (RA) has not been studied yet.
Gia Deyab +10 more
doaj +1 more source
Frontiers in Oncology, 2013 Proteoglycans and in particular the syndecans are involved in the differentiation process across the epithelial-mesenchymal axis, principally through their ability to bind growth factors and modulate their downstream signalling.
Tünde eSzatmári, Katalin eDobra
doaj +1 more source
Heparan sulfate proteoglycans undergo differential expression alterations in left sided colorectal cancer, depending on their metastatic character [PDF]
, 2018 Background Heparan sulfate proteoglycans (HSPGs) are complex molecules which play a role in the invasion and growth and metastatic properties of cancerous cells.
Castañón de la Torre, Sonia +6 more
core +2 more sources
Molecular Medicine, 2021 Background We investigated the feasibility of two biomarkers of endothelial damage (Syndecan-1 and thrombomodulin) in coronavirus disease 2019 (COVID-19), and their association with inflammation, coagulopathy, and mortality.
Dong Zhang +11 more
doaj +1 more source
Endothelial glycocalyx during early reperfusion in patients undergoing cardiac surgery.
PLoS ONE, 2021 BackgroundExperimental cardiac ischemia-reperfusion injury causes degradation of the glycocalyx and coronary washout of its components syndecan-1 and heparan sulfate.
Arie Passov +5 more
doaj +1 more source
Syndecan-1: A Quantitative Marker for the Endotheliopathy of Trauma [PDF]
Journal of the American College of Surgeons, 2017 BACKGROUND: Endothelial glycocalyx breakdown elicits syndecan-1 shedding and endotheliopathy of trauma (EoT). We hypothesized that a cutoff syndecan-1 level can identify patients with endothelial dysfunction who would have poorer outcomes.
Sisse R. Ostrowski +12 more
openaire +4 more sources
Detection of Syndecan-1 and Heparanase-1 Genes in Esophageal Carcinoma by Quantitative RT-PCR
Cancer Biology & Medicine, 2010 OBJECTIVE To quantitatively explore the expression of Syndecan-1 and heparanase-1 in esophageal cancer tissue as well as their relationship with the clinicopathological factors, in order to evaluate their roles in tumor invasion and metastasis.METHODS
Jun-li SI, Yu-qin QI, Jing-yuan CUI
doaj +1 more source