Results 41 to 50 of about 11,302 (215)

A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure [PDF]

, 2017
Aims: It is unclear whether distinct pathophysiological processes are present among patients with acute heart failure (AHF), with and without diabetes.
Bloomfield, Daniel M., Cleland, John G.F., Cotter, Gad, Davison, Beth A., Demissei, Biniyam G., Dittrich, Howard, Ezekowitz, Justin A., Givertz, Michael M., Hillege, Hans L., Khan, Mohsin A.F., Metra, Marco, O'Connor, Christopher M., Ponikowski, Piotr, Sharma, Abhinav, Teerlink, John R., Tromp, Jasper, van Veldhuisen, Dirk J., Voors, Adriaan A.   +17 more
core   +2 more sources

Molecular targets and signaling pathways regulated by nuclear translocation of syndecan-1

BMC Cell Biology, 2017
Background The cell-surface heparan sulfate proteoglycan syndecan-1 is important for tumor cell proliferation, migration, and cell cycle regulation in a broad spectrum of malignancies.
Tünde Szatmári, Filip Mundt, Ashish Kumar-Singh, Lena Möbus, Rita Ötvös, Anders Hjerpe, Katalin Dobra   +6 more
doaj   +1 more source

On Top of the Alveolar Epithelium: Surfactant and the Glycocalyx [PDF]

, 2020
Gas exchange in the lung takes place via the air-blood barrier in the septal walls of alveoli. The tissue elements that oxygen molecules have to cross are the alveolar epithelium, the interstitium and the capillary endothelium.
Hegermann, Jan, Kuebler, Wolfgang M., Lopez-Rodriguez, Elena, Matuszak, Jasmin, Nouailles, Geraldine, Ochs, Matthias, Simmons, Szandor, Timm, Sara, Witzenrath, Martin   +8 more
core   +1 more source

Targeting syndecan-1 in breast cancer inhibits osteoclast functions through up-regulation of osteoprotegerin

Journal of Bone Oncology, 2014
Background: Breast cancer often metastasizes into bone and leads to osteolytic lesions. The underlying mechanisms, however, are complex and not fully understood.
Peggy Benad-Mehner, Stefanie Thiele, Tilman D. Rachner, Andy Göbel, Martina Rauner, Lorenz C. Hofbauer   +5 more
doaj   +1 more source

MMP7 shedding of syndecan-1 facilitates re-epithelialization by affecting alpha(2)beta(1) integrin activation.

PLoS ONE, 2009
BackgroundLung injury promotes the expression of matrix metalloproteinase-7 (MMP7, matrilysin), which is required for neutrophil recruitment and re-epithelialization. MMP7 governs the lung inflammatory response through the shedding of syndecan-1. Because
Peter Chen, Laura E Abacherli, Samuel T Nadler, Ying Wang, Qinglang Li, William C Parks   +5 more
doaj   +1 more source

Interactions of syndecan-1 and heparin with human collagens [PDF]

Glycobiology, 1994
Glycosaminoglycan (GAG)-collagen interactions play important roles in cell adhesion and extracellular matrix assembly; however, the chemical bases for these interactions are not fully understood. We have used affinity co-electrophoresis (ACE) (Lee, M.K. and Lander, A.D., Proc. Natl. Acad.
San Antonio, James D, Karnovsky, Morris J, Gay, Steffen, Sanderson, Ralph D, Lander, Arthur D   +4 more
openaire   +4 more sources

Syndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells

Cell Communication and Signaling, 2020
Background Syndecans regulate cell migration thus having key roles in scarring and wound healing processes. Our previous results have shown that Thy-1/CD90 can engage both αvβ3 integrin and Syndecan-4 expressed on the surface of astrocytes to induce cell
Alejandra Valdivia, Areli Cárdenas, Marianne Brenet, Horacio Maldonado, Milene Kong, Jorge Díaz, Keith Burridge, Pascal Schneider, Alejandra San Martín, Rafael García-Mata, Andrew F. G. Quest, Lisette Leyton   +11 more
doaj   +1 more source

The utility of syndecan-1 circulating levels as a biomarker in patients with previous or active COVID-19: a systematic review and meta-analysis

BMC Infectious Diseases, 2023
Background With the emergence of coronavirus disease of 2019 (COVID-19), several blood biomarkers have been identified, including the endothelial biomarker syndecan-1, a surface proteoglycan.
Elina Ghondaghsaz, Amirmohammad Khalaji, Mitra Norouzi, Douglas D. Fraser, Sanam Alilou, Amir Hossein Behnoush   +5 more
doaj   +1 more source

Serum syndecan-1 concentration in hospitalized patients with heart failure may predict readmission-free survival

PLoS ONE, 2021
Syndecan-1 is found in the endothelial glycocalyx and is released into the bloodstream during stressed conditions, including severe diseases such as acute kidney injury, chronic kidney disease, and cardiovascular disease.
Yuichiro Kitagawa, Itta Kawamura, Keiko Suzuki, Hideshi Okada, Takuma Ishihara, Hiroyuki Tomita, Kodai Suzuki, Chihiro Takada, So Sampei, Soichiro Kano, Kohei Kondo, Hirotaka Asano, Yugo Wakayama, Ryo Kamidani, Yuki Kawasaki, Hirotsugu Fukuda, Ayane Nishio, Takahito Miyake, Tetsuya Fukuta, Ryu Yasuda, Hideaki Oiwa, Yoshinori Kakino, Nagisa Miyazaki, Takatomo Watanabe, Takahiro Yoshida, Tomoaki Doi, Akio Suzuki, Shozo Yoshida, Hitoshi Matsuo, Shinji Ogura   +29 more
doaj   +3 more sources

Syndecan expressions in the human amnion and chorionic plate

European Journal of Histochemistry, 2010
The syndecan family consists of four distinct membrane glycoproteins in mammals. Syndecans control cell proliferation, differentiation, adhesion and migration through participation in cell-cell interactions, anchorage of cells to the extracellular ...
T. Lorenzi, A. Turi, C. Crescimanno, M. Morroni, M. Castellucci, G. David, A. L. Tranquilli, D. Marzioni   +7 more
doaj   +1 more source