Results 111 to 120 of about 7,229,609 (313)

Advanced Datapath Synthesis using Graph Isomorphism [PDF]

open access: yesarXiv, 2017
This paper presents an advanced DAG-based algorithm for datapath synthesis that targets area minimization using logic-level resource sharing. The problem of identifying common specification logic is formulated using unweighted graph isomorphism problem, in contrast to a weighted graph isomorphism using AIGs.
arxiv  

The roles and applications of extracellular vesicles in cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

Program Synthesis is $Σ_3^0$-Complete [PDF]

open access: yesarXiv
This paper considers program synthesis in the context of computational hardness, asking the question: How hard is it to determine whether a given synthesis problem has a solution or not? To answer this question, this paper studies program synthesis for a basic imperative, Turing-complete language IMP, for which this paper proves that program ...
arxiv  

m-Order Time Optimal Control Synthesis Function of Discrete System [PDF]

open access: yesarXiv, 2019
In this paper, first of all, we introduce the basic concepts of generating function in combinatorics and some combinatorial identities. In order to facilitate the understanding of m-order time optimal control synthesis function of discrete system (referred as m-order synthesis function), secondly, we introduce the derivation process and control ideas ...
arxiv  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Quantum State Synthesis: Relation with Decision Complexity Classes and Impossibility of Synthesis Error Reduction [PDF]

open access: yesarXiv
This work investigates the relationships between quantum state synthesis complexity classes (a recent concept in computational complexity that focuses on the complexity of preparing quantum states) and traditional decision complexity classes. We especially investigate the role of the synthesis error parameter, which characterizes the quality of the ...
arxiv  

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Entry to 2-aminoprolines via electrochemical decarboxylative amidation of N‑acetylamino malonic acid monoesters

open access: yesBeilstein Journal of Organic Chemistry
The electrochemical synthesis of 2-aminoprolines based on anodic decarboxylation–intramolecular amidation of readily available N-acetylamino malonic acid monoesters is reported. The decarboxylative amidation under Hofer–Moest reaction conditions proceeds
Olesja Koleda   +5 more
doaj   +1 more source

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