Results 81 to 90 of about 7,336,560 (297)

Catalytic Performance of HZSM-5–Al2O3 Nanocomposites in Glycerol Conversion

International Journal of Chemical Engineering
The effect of the components’ ratio in HZSM-5–Al2O3 compositions on their acidic and catalytic characteristics during glycerol transformation was investigated.
Nina V. Vlasenko, Oleksii O. Zhokh, Valentina I. Gritsenko, Peter E. Strizhak   +3 more
doaj   +1 more source

Genetic inactivation of the sigma-1 chaperone protein results in decreased expression of the R2 subunit of the GABA-B receptor and increased susceptibility to seizures

Neurobiology of Disease, 2021
There is a growing body of evidence demonstrating the significant involvement of the sigma-1 chaperone protein in the modulation of seizures. Several sigma-1 receptor (Sig1R) ligands have been demonstrated to regulate the seizure threshold in acute and ...
Edijs Vavers, Baiba Zvejniece, Gundega Stelfa, Baiba Svalbe, Karlis Vilks, Einars Kupats, Rudolfs Mezapuke, Lasma Lauberte, Maija Dambrova, Liga Zvejniece   +9 more
doaj  

Early Terrestrial Conditions That May Have Favored Organic Synthesis [PDF]

, 1908
T. C. Chamberlin, Rollin T. Chamberlin
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

The synthesis of peptides related to gramicidin S and the significance of optical configuration in antibiotic peptides. 1. Tripeptides [PDF]

, 1950
J. Ieuan Harris, T. S. Work
openalex   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Direct Observations of Twin Formation Dynamics in Binary Semiconductors

ACS Nanoscience Au, 2021
Marcus Tornberg, Robin Sjökvist, Krishna Kumar, Christopher R. Andersen, Carina B. Maliakkal, Daniel Jacobsson, Kimberly A. Dick   +6 more
doaj   +1 more source

ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. INFLUENCE OF BACTERIOPHAGE T2 ON THE SYNTHETIC PATHWAY IN HOST CELLS [PDF]

, 1959
Arthur Kornberg, Steven B. Zimmerman, S.R. Kornberg, John Josse   +3 more
openalex   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

CXXVII.—Isolation and synthesis of p-hydroxyphenylethylamine, an active principle of ergot soluble in water [PDF]

, 1909
George Barger
openalex   +1 more source