Results 121 to 130 of about 1,525,936 (258)

Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT

open access: yesAdvanced Science, EarlyView.
Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao   +9 more
wiley   +1 more source

Comparison of antioxidant capacities of natural and synthetic antioxidant compounds [PDF]

open access: yes, 2011
Bu çalışmada sentetik ve doğal antioksidan bileşiklerin beş farklı yöntemle in vitro antioksidan aktiviteleri ölçülmüş ve karşılaştırılmıştır. Sentetik antioksidanları temsil etmek üzere bütillenmiş hidroksianisol (BHA), bütillenmiş hidroksitoluen (BHT),
Yavaşer, Rukiye
core  

Synthetic Biology of Antimicrobial Discovery

open access: yes, 2012
Antibiotic discovery has a storied history. From the discovery of penicillin by Sir Alexander Fleming to the relentless quest for antibiotics by Selman Waksman, the stories have become like folklore used to inspire future generations of scientists ...
Zakeri, Bijan, Lu, Timothy K.
core   +1 more source

The Effect of Grape Seed Extract on Lipid Oxidation, Color Change, and Microbial Growth in a Beef–Pork Sausage Model System

open access: yesMolecules
The effect of various natural antioxidants—grape seed extract (GSE), ascorbic acid (AA), α-tocopherol (TP), a combination of GSE and AA, and a combination of GSE and TP—on pH, water activity, color change, lipid oxidation, antioxidant capacity, total ...
Yavor Ivanov   +3 more
doaj   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

open access: yesAdvanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang   +12 more
wiley   +1 more source

Analysis of Synthetic Antioxidant in Food by Capillary Electrophoresis

open access: yes, 2011
A capillary electrophoretic assay for determining synthetic antioxidant butylated hydroxyanisole in food has been developed. The extraction with 70% (v/v) methanol quantitatively extracted synthetic antioxidant.
Ying Gao, Qian Xiang
core   +1 more source

Celastrol‐Loaded Conductive Hydrogel Mitigates Myocardial Ischemia‐Reperfusion Injury and Restores Electrophysiological Function

open access: yesAdvanced Science, EarlyView.
Schematic illustration of the Pluronic F127 diacrylate/gelatin methacryloyl/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate)/celastrol hydrogel (FGPC) for localized myocardial ischemia–reperfusion injury treatment. FGPC combines sustained celastrol delivery with PEDOT:PSS‐mediated conductive support to attenuate acute oxidative/inflammatory ...
Shixin Wang   +10 more
wiley   +1 more source

Development of Solid formulation containing Natural herbs with High Antioxidant Activity

open access: yes, 2020
This research aims to investigate HPMC capsules containing natural herbs with high antioxidant activity. We want to develop HPMC capsules containing Trigonella foenum-graecum (Fenugreek), Silybum marianum (Milk thistle) and Paprika and investigate their ...
Madugba, Princess
core  

Exploring the antioxidant potential of nekemias species extracts on edible oils: In vitro assessment and lipid oxidation inhibition

open access: yesHeliyon
Synthetic antioxidants have long been used to protect edible oils from oxidation. However, concerns about their potential health risks and environmental impact have led to a growing interest in natural antioxidants.
Yuan Zeng   +5 more
doaj   +1 more source

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