Results 141 to 150 of about 1,044,115 (187)

Beyond synthetic lethality in large-scale metabolic and regulatory network models via genetic minimal intervention set. [PDF]

Bioinform Adv
Barrena N, Rodriguez-Flores C, Valcárcel LV, Olaverri-Mendizabal D, Agirre X, Prósper F, Planes FJ.   +6 more
europepmc   +1 more source

Concept of Synthetic Lethality in Cancer

World Journal of Dentistry, 2016
openaire   +1 more source

MVGAE: A Multi-View Graph Auto-Encoder Model for Drug Prediction of Non-Small Cell Lung Cancer Based on Synthetic Lethality. [PDF]

Curr Issues Mol Biol
Hu S, Jiang R, Zhao N.
europepmc   +1 more source

Computationally-designed aptamers targeting RAD51-BRCA2 interaction impair homologous recombination and induce synthetic lethality. [PDF]

Nat Commun
Milordini G, Zacco E, Masi M, Armaos A, Di Palma F, Oneto M, Gilodi M, Rupert J, Broglia L, Varignani G, Scotto M, Marotta R, Girotto S, Cavalli A, Tartaglia GG.   +14 more
europepmc   +1 more source

Targeting miR-4653-3p/SLC25A51/SIRT3 axis to induce synthetic lethality in ARID1A-deficient colorectal cancer via blockade of DNA repair. [PDF]

J Transl Med
Lin X, Wu C, Wu D, Qin W, Zeng Y, Song Y, Xiang L, Shim JS, Liu S, Li A.   +9 more
europepmc   +1 more source

Correction to: Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer. [PDF]

Protein Cell
europepmc   +1 more source

Exploiting Synthetic Lethality of PRMT5 for Precision Treatment of MTAP-Deficient Glioblastoma. [PDF]

Int J Transl Med (Basel)
Nguyen TTT, Yi E, Badr CE.
europepmc   +1 more source

A fast method for extracting essential and synthetic lethality genes in GEM models. [PDF]

Bioinform Adv
Guil F, García JM.
europepmc   +1 more source

Synthetic lethality from the combination of a histone methyltransferase SUV39H2 inhibitor and a poly (ADP-ribose) polymerase inhibitor for uterine leiomyosarcoma. [PDF]

BMC Cancer
Toyohara Y, Sone K, Kumegawa K, Yamamoto Y, Hachijo R, Kukita A, Taguchi A, Ikemura M, Miyamoto Y, Tanikawa M, Iriyama T, Mori M, Hamamoto R, Ushiku T, Oda K, Hirota Y, Maruyama R, Osuga Y.   +17 more
europepmc   +1 more source