Replication protein A protects lagging strand gaps, restricting PARP inhibitor-induced synthetic lethality in BRCA1-deficient tumors. [PDF]
VanderVere-Carozza PS +5 more
europepmc +1 more source
Establishment of novel cholangiocarcinoma cell lines with ARID1A deficiency and preclinical validation of synthetic lethality therapies. [PDF]
Prasopporn S +10 more
europepmc +1 more source
Beyond synthetic lethality in large-scale metabolic and regulatory network models via genetic minimal intervention set. [PDF]
Barrena N +6 more
europepmc +1 more source
Correction to: Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer. [PDF]
europepmc +1 more source
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