Results 1 to 10 of about 271,195 (312)
Molbank, 2021 In the present work, construction of double-charged cationic amphiphilic 1,1′-{[3,5-bis(dodecyl¬oxy-carbonyl)-4-(thiophen-3-yl)-1,4-dihydropyridine-2,6-diyl]bis-(methylene)}bis(pyridin-1-ium) dibromide (7) was performed in four steps.
Martins Rucins +6 more
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Molbank, 2022 Synthesis of a double-charged cationic amphiphilic 1,4-dihydropyridine derivative with dodecyl ester groups at positions 3 and 5 of the 1,4-DHP ring was performed starting from Hantzsch type cyclization of dodecyl acetoacetate, 2-naphthaldehyde and ...
Martins Rucins +5 more
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Lipid sponge droplets as programmable synthetic organelles [PDF]
Proceedings of the National Academy of Sciences, 2020 Significance Organelles spatially and temporally orchestrate biochemical reactions in a cell to a degree of precision that is still unattainable in synthetic reaction systems. Additionally, organelles such as the endoplasmic reticulum (ER) contain highly interconnected and dense membrane networks that provide large reaction spaces for
Bhattacharya, Ahanjit +8 more
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Synthesis, self-assembly and lipoplex formulation of two novel cyclic phosphonate lipids [PDF]
QScience Connect, 2013 Background: Synthetic cationic lipids hold much potential as gene packaging and delivery agents for the treatment of inherited and acquired life threatening diseases, such as cancer, AIDS, cardiovascular diseases, and certain autoimmune disorders ...
JenniferYeh +4 more
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Somnogenic activities of synthetic lipid A [PDF]
Infection and Immunity, 1989 Bacterial infections and various immune response modifiers, including endotoxin and its lipid A moiety, alter sleep duration. The purpose of this study is to amplify our understanding of lipid A structure-somnogenic-pyrogenic activity relationships.
A B, Cady +4 more
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Synthetic Lipid Nanoparticles Targeting Steroid Organs [PDF]
Journal of Nuclear Medicine, 2013 Lipidots are original nanoparticulate lipid delivery vectors for drugs and contrast agents made from materials generally regarded as safe. Here, we characterized the in vivo stability, biodistribution, and pharmacokinetics of lipidots.Lipidots 55 nm in diameter and coated with a phospholipid/poly(ethyleneglycol) surfactant shell were triply labeled ...
Juliette, Mérian +5 more
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Synthesis of ether lipids: natural compounds and analogues
Beilstein Journal of Organic Chemistry, 2023 Ether lipids are compounds present in many living organisms including humans that feature an ether bond linkage at the sn-1 position of the glycerol. This class of lipids features singular structural roles and biological functions. Alkyl ether lipids and
Marco Antônio G. B. Gomes +7 more
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Bioactive Ether Lipids: Primordial Modulators of Cellular Signaling
Metabolites, 2021 The primacy of lipids as essential components of cellular membranes is conserved across taxonomic domains. In addition to this crucial role as a semi-permeable barrier, lipids are also increasingly recognized as important signaling molecules with diverse
Nikhil Rangholia +2 more
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BMC Pulmonary Medicine, 2021 Background Optimal functionality of synthetic lung surfactant for treatment of respiratory distress syndrome in preterm infants largely depends on the quality and quantity of the surfactant protein B (SP-B) peptide mimic and the lipid mixture.
Frans J. Walther +3 more
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Straightforward synthesis of cytosporone analogs AMS35AA and AMS35BB
Anais da Academia Brasileira de Ciências, 2021 Cytosporones, a class of octaketide resorcinolic lipids, have drawn the attention of researchers for exhibiting a number of notable biological properties.
NEIMAR VITOR +5 more
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