Results 71 to 80 of about 911,338 (260)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Enantioconvergent catalysis

Beilstein Journal of Organic Chemistry, 2016
An enantioconvergent catalytic process has the potential to convert a racemic starting material to a single highly enantioenriched product with a maximum yield of 100%.
Justin T. Mohr, Jared T. Moore, Brian M. Stoltz   +2 more
doaj   +1 more source

Efficient Synthesis of an Aluminum Amidoborane Ammoniate

Energies, 2015
A novel species of metal amidoborane ammoniate, [Al(NH2BH3)63−][Al(NH3)63+] has been successfully synthesized in up to 95% via the one-step reaction of AlH3·OEt2 with liquid NH3BH3·nNH3 (n = 1~6) at 0 °C.
Junzhi Yang, Paul R. Beaumont, Terry D. Humphries, Craig M. Jensen, Xingguo Li   +4 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

A general and atom-efficient continuous-flow approach to prepare amines, amides and imines via reactive N-chloramines

Beilstein Journal of Organic Chemistry, 2018
Chloramines are an important class of reagents, providing a convenient source of chlorine or electrophilic nitrogen. However, the instability of these compounds is a problem which makes their isolation and handling difficult. To overcome these hazards, a
Katherine E. Jolley, Michael R. Chapman, A. John Blacker   +2 more
doaj   +1 more source

Comparison of Synthetic Methods and Identification of Several Artificial Antigens of Deoxynivalenol. [PDF]

Molecules, 2023
Han L, Li Y, Jiang J, Liu C, Hou J, Wang B, Wang Z.   +6 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

A Paternò–Büchi Reaction of Aromatics with Quinones under Visible Light Irradiation

Molecules
Reported herein is a Paternò–Büchi reaction of aromatic double bonds with quinones under visible light irradiation. The reactions of aromatics with quinones exposed to blue LED irradiation yielded oxetanes at −78 °C, which was attributed to both the ...
Wen-Wen Li, Jia-Lin Zhao, Ze-Yu Wang, Pei-Ting Li, Zi-Fa Shi, Xiao-Ping Cao, Qiang Liu   +6 more
doaj   +1 more source

Hydroxy- and Amino-Phosphonates and -Bisphosphonates: Synthetic Methods and Their Biological Applications. [PDF]

Front Chem, 2022
Kaboudin B, Daliri P, Faghih S, Esfandiari H.   +3 more
europepmc   +1 more source

synthetic method

Citation: 'synthetic method' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15364 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source