Results 131 to 140 of about 811,099 (302)

Systematic reviews: a cross-sectional study of location and citation counts

BMC Medicine, 2003
Background Systematic reviews summarize all pertinent evidence on a defined health question. They help clinical scientists to direct their research and clinicians to keep updated.
Morgan Douglas, Wilczynski Nancy L, Montori Victor M, Haynes R Brian   +3 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The searchbuildR shiny app: A new implementation of the objective approach for search strategy development in systematic reviews

Cochrane Evidence Synthesis and Methods
Introduction One of the main tasks in information retrieval is the development of Boolean search strategies for systematic searches in bibliographic databases. This includes the identification of free‐text terms and controlled vocabulary.
Claudia Kapp, Naomi Fujita‐Rohwerder, Jona Lilienthal, Wiebke Sieben, Siw Waffenschmidt, Elke Hausner   +5 more
doaj   +1 more source

Traditional Chinese Medicine for childhood obesity: an umbrella review of systematic reviews and meta-analyses

Frontiers in Medicine
BackgroundChildhood obesity is a major global public health concern associated with adverse cardiometabolic outcomes and long-term health risks. While conventional treatments such as diet, exercise, and behavioral therapy remain the cornerstone of ...
Yuanyuan He, Shixin Zhuang, Zhanna Zhussupova, Nadiar M. Mussin, Yiqun Zhang, Jian Yu, Amin Tamadon   +6 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Music Therapy for Managing Dental Anxiety in Children: A Systematic Review and Meta-Analysis of Clinical Evidence

Children
Background: Dental anxiety is a common challenge in paediatric dentistry, often leading to avoidance of treatment and compromised oral health. Non-pharmacological interventions such as music therapy have gained increasing attention as safe and cost ...
Laura Marqués-Martínez, Jorge Andrés, Esther García-Miralles, Carla Borell-García, Juan Ignacio Aura-Tormos, Clara Guinot Barona   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Dietary fiber consumption and outcomes of different cancers: an umbrella review

Food & Nutrition Research
Background: The relationship between dietary fiber intake and cancer outcomes, including incidence, recurrence, and mortality, is crucial for understanding cancer prevention strategies.
Xingyu He, Jiayi Hou, Lei Liu, Xin Chen, Lijie Zhang, Caojia Pang, Yu Tong, Hongling Li, Feng Chen, Rong Peng, Zheng Shi   +10 more
doaj   +1 more source

Towards Evidence-Based Sustainable Communities: Report on Survey of Urban Sustainability Centers in U.S. Universities [PDF]

, 2011
Provides an overview of characteristics of urban sustainability research centers, including organizational structure, personnel capacity, finances, current objectives, and recent research topics.
Genevieve Giuliano, Hilda Blanco
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