Results 101 to 110 of about 22,875,861 (325)

Ecological indicators for abandoned mines, Phase 1: Review of the literature [PDF]

, 2009
Mine waters have been identified as a significant issue in the majority of Environment Agency draft River Basin Management Plans. They are one of the largest drivers for chemical pollution in the draft Impact Assessment for the Water Framework Directive (
Jarvis, A. P., Kelly, M. G., Lofts, S., Merrix, F. L., Ormerod, S. J., Tipping, E.   +5 more
core  

Transparency and translation of science in a modern world [PDF]

, 2013
The co-Editors-in-Chief of Environmental Health respond to an unusual initiative taken by editors of 14 toxicology journals to influence pending decisions by the European Commission to establish a framework for regulating chemicals that pose a hazard to ...
Grandjean, Philippe, Ozonoff, David
core   +1 more source

Increased Anti‐Psoriatic Effect of Anti‐Inflammatory Dendrimers Using Fluid Catanionic Vesicle‐Based Topical Formulations

Advanced Healthcare Materials, EarlyView.
Next‐Generation Psoriasis Therapy – With advanced dendrimer‐based formulations, this study paves the way for highly effective, skin‐permeable treatments. Encapsulated in fluid catanionic vesicles, IMD‐006 and its analogues show promising anti‐psoriatic effects offering a targeted, non‐invasive approach to managing chronic skin inflammation.
Ranime Jebbawi, Abdelouahd Oukhrib, Emily Clement, Hélène Labie, Stéphanie Cassel, Séverine Fruchon, Anne‐Marie Caminade, Michel Simon, Rémy Poupot, Cédric‐Olivier Turrin, Muriel Blanzat   +10 more
wiley   +1 more source

Antidote application: an educational system for treatment of common toxin overdose [PDF]

, 2017
Poisonings account for almost 1% of emergency room visits each year. Time is a critical factor in dealing with a toxicologic emergency. Delay in dispensing the first antidote dose can lead to life-threatening sequelae.
Brusic, V., Chitkushev, L., Long, J., Zhang, G., Zhang, Y.   +4 more
core  

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

Toxicity of Dietary Exposure to 3-Monochloropropanediol, Glycidol, and Their Fatty Acid Esters

Journal of Food Quality
3-Monochloropropane-1,2-diol (3-MCPD), 2,3-epoxy-1-propanol (glycidol), and their fatty acid esters are heat-induced food toxicants that have widely been investigated. This review study presents an overview of current knowledge about the dietary toxicity
Daniel Sitsofe Yabani, Isaac Williams Ofosu, Gloria Mathanda Ankar-Brewoo, Herman Erick Lutterodt   +3 more
doaj   +1 more source

Exploring the potential anti-senescence effects of soybean-derived peptide Soymetide in mice hippocampal neurons via the Wnt/β-catenin pathway

Frontiers in Pharmacology
Soybean-based foods enhance cognitive functions by influencing hippocampal mechanisms. These salutary effects have so far been attributed to isoflavones present in soybeans.
Asmita Garg, Asmita Garg, Jyotshana Saroj, Jyotshana Saroj, Saurabh Tiwari, Saurabh Tiwari, Uttara Das, Uttara Das, Neetu Shukla, Neetu Shukla, Jimut Kanti Ghosh, Jimut Kanti Ghosh, Sanghamitra Bandyopadhyay, Sanghamitra Bandyopadhyay   +13 more
doaj   +1 more source

A survey of chemical information systems [PDF]

A survey of the features, functions, and characteristics of a fairly wide variety of chemical information storage and retrieval systems currently in operation is given.
Dominick, Wayne D., Shaikh, Aneesa Bashir   +1 more
core   +1 more source

Natural Sweetener Stevioside‐Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia

Advanced Healthcare Materials, EarlyView.
This study addresses limitations of minoxidil (MXD) in treating androgenetic alopecia by using stevioside (STV) as a solubilizing agent and microneedle (MN) material. STV enhanced MXD's solubility and skin absorption, leading to improved drug delivery and significant hair regrowth in animal models, demonstrating strong potential for AGA treatment ...
Junying Zhang, Tianyu Shao, Hailiang Li, Luying Zhu, Lamyaa Albakr, Nial J. Wheate, Lifeng Kang, Chungyong Wu   +7 more
wiley   +1 more source

Lipidome atlas of p53 mutant variants in pancreatic cancer

Biology Direct
Mutations in the tumour suppressor protein p53 are present in 70% of human pancreatic ductal adenocarcinomas (PDAC), subsequently to highly common activation mutation of the oncogene KRAS. These p53 mutations generate stable expression of mutant proteins,
Kian Cotton, Charley Comer, Sabrina Caporali, Alessio Butera, Stephanie Gurres, Francesco Capradossi, Angelo D’Alessandro, Ivano Amelio, Maria Victoria Niklison-Chirou   +8 more
doaj   +1 more source