Results 71 to 80 of about 323,783 (333)

A Network Toxicology Approach for Mechanistic Modelling of Nanomaterial Hazard and Adverse Outcomes

Advanced Science
Hazard assessment is the first step in evaluating the potential adverse effects of chemicals. Traditionally, toxicological assessment has focused on the exposure, overlooking the impact of the exposed system on the observed toxicity.
Giusy del Giudice, Angela Serra, Alisa Pavel, Marcella Torres Maia, Laura Aliisa Saarimäki, Michele Fratello, Antonio Federico, Harri Alenius, Bengt Fadeel, Dario Greco   +9 more
doaj   +1 more source

Differential bioreactivity of neutral, cationic and anionic polystyrene nanoparticles with cells from the human alveolar compartment: robust response of alveolar type 1 epithelial cells [PDF]

, 2015
BACKGROUND: Engineered nanoparticles (NP) are being developed for inhaled drug delivery. This route is non-invasive and the major target; alveolar epithelium provides a large surface area for drug administration and absorption, without first pass ...
Ruenraroengsak, P, Tetley, TD
core   +2 more sources

Spin‐Dependent Generation of Surface‐Bound Radicals Toward Selective and Long‐Lasting Water Purification

Advanced Functional Materials, EarlyView.
This study develops a novel atomic engineering strategy to fine‐tune the spin state of α‐Fe2O3 catalysts toward a medium‐spin state, thereby modulating peroxymonosulfate activation and selectively yielding surface‐bound radicals. Compared with free radicals, surface‐bound radicals exhibit moderated oxidation potential, extended lifespan, surface ...
Shuyu Wang, Zhonglin Chen, Jimin Shen, Pengwei Yan, Jing Kang, Binyuan Wang, Shengxin Zhao, Xiaoguang Duan   +7 more
wiley   +1 more source

The systems toxicology challenge

Proceedings of the 6th ACM Conference on Bioinformatics, Computational Biology and Health Informatics, 2015
Risk assessment in the context of 21st century toxicology relies on the elucidation and understanding of mechanisms of toxicity. For that purpose, datasets generated by high-throughput technologies (e.g., high-throughput/content screening) combined with various omics data types are now generated in vitro to test large and diverse set of chemicals (e.g.
Poussin, Carine, Belcastro, Vincenzo, Boue, Stéphanie, Martin, Florian, Sewer, Alain, Bjoern Titz, Ivanov, Nikolai, Hoeng, Julia, Peitsch, Manuel C   +8 more
openaire   +2 more sources

Isolation of a Stenotrophomonas strain and identification of methyltransferase genes conferring the high arsenic volatilizing ability

Applied and Environmental Microbiology
Microbial arsenic (As) volatilization plays a significant role in the global As biogeochemical cycle and presents a promising approach for bioremediation. In this study, an autotrophic strain of Stenotrophomonas maltophilia was isolated from sewage water
Diksha Singh, Nitish Sharma, Sheetal Agarwal, Sadaf Aiman Khan, Veena Jain, Sukhveer Singh, Somendu Roy, Kusum Yadav, Sudhir Pratap Singh, Vikas Srivastava   +9 more
doaj   +1 more source

Genotoxicity and Cytotoxicity Exerted by Pesticides in Different Biotic Matrices-An Overview of More Than a Decade of Experimental Evaluation [PDF]

, 2014
Agrochemicals represent one of the most important sources of environmental pollution. Although attempts to reduce agrochemical use through organic agricultural practices and the use of other technologies to control pests continue, the problem is still
Larramendy, Marcelo Luis, Nikoloff, Noelia, Ruiz de Arcaute, Celeste, Soloneski, Sonia Maria Elsa   +3 more
core   +2 more sources

Laser Engineering of HfN‐Based Nanoparticles for Safe NIR‐I Photothermal and X‐ray Enhancing Cancer Therapies

Advanced Functional Materials, EarlyView.
In this study, we produced HfN‐based nanoparticles via femtosecond laser ablation in acetone. The nanoparticles exhibit a red‐shifted plasmonic resonance in the NIR‐I window, colloidal stability after coating with polyethyleneglycol, and excellent biocompatibility. The photothermal and X‐ray sensitization therapeutic effects were demonstrated for tumor
Julia S. Babkova, Ivan V. Zelepukin, Lyubov V. Gorelik, Anton L. Popov, Andrei I. Pastukhov, Gleb V. Tikhonowski, Maxim S. Savinov, Danil D. Kolmanovich, Nikita A. Pivovarov, Alina Yu. Kapitannikova, Anton A. Popov, Anna S. Sogomonyan, Vsevolod A. Skribitsky, Aziz B. Mirkasymov, Andrei V. Kabashin, Sergey M. Deyev   +15 more
wiley   +1 more source

Integrative assessment of RNA sequencing and in silico analysis to pinpoint mRNAs, lncRNAs, and circRNAs interactions with miRNAs underlying arsenic-induced neurotoxicity

BMC Genomics
Background The acquisition of neurodegeneration hallmarks necessitates molecular changes at multiple levels of functional genomics. Regulatory RNAs, including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), play crucial ...
Sana Sarkar, Anuj Pandey, Bushra Khan, A. B. Pant   +3 more
doaj   +1 more source

Where Most Frameworks Degrade: Flexible Bimetallic Phosphonate Crystals as pH‐Universal Supercapacitor Electrodes

Advanced Functional Materials, EarlyView.
Plastically flexible single crystals of the bimetallic phosphonate framework [Cu(2,2′‐bpy)VO(O3PC6H5)2] combine mechanical adaptability with robust pseudocapacitive charge storage. The material delivers about 140 Fg−1 at pH 4 and pH 10 and remains stable across pH 2‐12, enabling energy storage under comparatively mild electrolyte conditions.
Tim Müller, Jean G. A. Ruthes, Biswajit Battacharya, Dorothee Silbernagl, Patrik Tholen, Aysenur Limon, Gülsüm Kinik, Christoph Janiak, Markus Suta, Franziska Emmerling, Volker Presser, Gündoğ Yücesan   +11 more
wiley   +1 more source

Relations of environmental contaminants, algal toxins, and diet with the reproductive success of American alligators on Florida Lakes [PDF]

, 2001
(113 page ...
Arnold, Beverly S., Gross, Timothy S., McDonald, Kelly, Spulveda, Maria S.   +3 more
core