Results 71 to 80 of about 108,508 (278)

Integrative assessment of RNA sequencing and in silico analysis to pinpoint mRNAs, lncRNAs, and circRNAs interactions with miRNAs underlying arsenic-induced neurotoxicity

BMC Genomics
Background The acquisition of neurodegeneration hallmarks necessitates molecular changes at multiple levels of functional genomics. Regulatory RNAs, including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), play crucial ...
Sana Sarkar, Anuj Pandey, Bushra Khan, A. B. Pant   +3 more
doaj   +1 more source

Isolation of a Stenotrophomonas strain and identification of methyltransferase genes conferring the high arsenic volatilizing ability

Applied and Environmental Microbiology
Microbial arsenic (As) volatilization plays a significant role in the global As biogeochemical cycle and presents a promising approach for bioremediation. In this study, an autotrophic strain of Stenotrophomonas maltophilia was isolated from sewage water
Diksha Singh, Nitish Sharma, Sheetal Agarwal, Sadaf Aiman Khan, Veena Jain, Sukhveer Singh, Somendu Roy, Kusum Yadav, Sudhir Pratap Singh, Vikas Srivastava   +9 more
doaj   +1 more source

Job satisfaction and rate of return on investment among pharmacology and toxicology PhD graduates in Iran: A cross-sectional study [PDF]

Research and Development in Medical Education
Background: Job satisfaction has a profound impact on productivity, retention, and overall performance in specialized fields such as pharmacology and toxicology. Understanding the determinants of job satisfaction and the rate of return on investment (ROR)
Sevda Shayesteh, Yasaman Alsadat Seyed Rezaei, Seyede Ghazale Angaji, Zahra Sharif, Reza Shahi   +4 more
doaj   +1 more source

Moving towards predictive toxicology - a systems biology approach [PDF]

, 2012
Human health and the environment are at risk of being exposed to a large number of hazardous chemicals each day. Unfortunately, many of these chemicals have no or little recorded toxicity information.
Antczak, Philipp
core  

Systems Biology Approaches in Pharmacology and Toxicology

, 2017
The on-going integration of systems biology functionalities into all aspects of pharmacology and toxicology has resulted in a more network-based focus, which continues to enhance the understanding of therapeutic efficacious and adverse events both at the
Dale E. Johnson
core   +1 more source

N, S Co‐Doped Carbon Quantum Dots‐Riboflavin Composite Photosensitizers for Enhanced Iontophoresis‐Assisted Corneal Cross‐Linking

Advanced Science, EarlyView.
This study explores the use of N, S co‐doped carbon quantum dots (NS‐CQDs) as carriers for riboflavin, creating NS‐CQDs‐RF composite photosensitizers. These composites improve riboflavin absorption, enhance ROS generation efficiency, and preserve corneal epithelium integrity.
Tinghong Xu, Yong Liu, Wenjing Zhang, Qiuruo Jiang, Yi Jin, Liangzheng Lin, Lumeng Wang, Zhanhao Gu, Mimi Lin, Shihao Chen   +9 more
wiley   +1 more source

Systems biology in toxicology and environmental health

, 2015
Systems Biology in Environmental Health: From the Genome to the Epigenome brings a systems biological perspective to recent findings that link environmental exposures to human disease.
Fry, Rebecca C.
core  

Databases Facilitating Systems Biology Approaches in Toxicology

, 2017
The on-going enhancement of information sources and tools to augment the understanding of chemical toxicity in human and environmental systems is a critical aspect of systems toxicology.
Ann M. H. Heslin, Dale E. Johnson
core   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source