Results 71 to 80 of about 320,373 (282)

Molecular biomarkers and toxic consequences of impact by organic pollution in aquatic organisms [PDF]

open access: yes, 1994
Organic contaminants are readily bioaccumulated by aquatic organisms. Exposure to and toxic effects of contaminants can be measured in terms of the biochemical responses of the organisms (i.e. molecular biomarkers).
Förlin, L.   +2 more
core  

Of Frogs & Rhetoric: The Atrazine Wars [PDF]

open access: yes, 2015
In a scientific dispute over the effects of atrazine on amphibians, chemical industry–funded and publically funded scientists present stunningly contrasting constructions of atrazine\u27s environmental concentrations, persistence, and potential to harm ...
Reeves, Carol
core   +2 more sources

Viral Infection‐Inspired Autonomous Detection of Fusion‐Competent Viruses for Screening and Environmental Surveillance

open access: yesAdvanced Materials, EarlyView.
Inspired by viral entry mechanisms, the FUSION assay enables autonomous detection of respiratory viruses via membrane fusion–triggered CRISPR‐Cas13a activation. VEACON selectively fuses with fusion‐competent viruses, triggering fluorescence within confined vesicles.
Jae Chul Park   +15 more
wiley   +1 more source

Integrative assessment of RNA sequencing and in silico analysis to pinpoint mRNAs, lncRNAs, and circRNAs interactions with miRNAs underlying arsenic-induced neurotoxicity

open access: yesBMC Genomics
Background The acquisition of neurodegeneration hallmarks necessitates molecular changes at multiple levels of functional genomics. Regulatory RNAs, including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), play crucial ...
Sana Sarkar   +3 more
doaj   +1 more source

Genotoxicity and Cytotoxicity Exerted by Pesticides in Different Biotic Matrices-An Overview of More Than a Decade of Experimental Evaluation [PDF]

open access: yes, 2014
Agrochemicals represent one of the most important sources of environmental pollution. Although attempts to reduce agrochemical use through organic agricultural practices and the use of other technologies to control pests continue, the problem is still
Larramendy, Marcelo Luis   +3 more
core   +2 more sources

Multifunctional Bio‐Based Packaging for Perishable Foods: Structural Design, Scalable Fabrication, and Versatile Applications

open access: yesAdvanced Materials, EarlyView.
An overview of design principles and scalable fabrication strategies for multifunctional bio‐based packaging. Radiative cooling films, modified‐atmosphere films/membranes, active antimicrobial/antioxidant platforms, intelligent optical/electrochemical labels, and superhydrophobic surfaces are co‐engineered from material chemistry to mesoscale structure
Lei Zhang   +6 more
wiley   +1 more source

Aerospace Medicine and Biology: A continuing bibliography, supplement 216 [PDF]

open access: yes
One hundred twenty reports, articles, and other documents introduced into the NASA scientific and technical information system in January 1981 are listed.

core   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

open access: yesAdvanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou   +5 more
wiley   +1 more source

Targeting TDP-43 Proteinopathy in hiPSC-Derived Mutated hNPCs with Mitoxantrone Drugs and miRNAs

open access: yesPharmaceutics
Background/Objectives: TDP-43 mutation-driven Amyotrophic Lateral Sclerosis (ALS) motor neuron disease is one of the most prominent forms (approximately 97%) in cases of sporadic ALS.
Uzair A. Ansari   +7 more
doaj   +1 more source

Toxicology of the respiratory system

open access: yesFolia Pharmacologica Japonica, 2009
呼吸器は,空気から酸素を取り入れ血液から二酸化炭素を放出するガス交換を行うための器官である.空気中に存在す化学物質は呼吸を通して体内に入るため,呼吸器はこれらの化学物質に最初に接触しその影響を最も受けやすい器官である.このため,大気汚染物質による健康障害では呼吸器が標的器官となることが多い.医薬品の分野では,吸入以外の経路でも抗癌剤等による薬剤性肺障害の報告があり,本誌でも詳しい総説がある(1).また,近年は経鼻投与など経気道的に投与する薬剤の実用化が進んでおり,医薬品の開発に際して鼻腔などの気道を含む呼吸器への直接的な接触による副作用が課題になってきている.本稿では,鼻腔等の気道を中心として,呼吸器の構造と機能,呼吸器毒性の検査法,薬剤等による呼吸器毒性について概説する.
openaire   +3 more sources

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