Results 81 to 90 of about 22,875,861 (325)

Differential bioreactivity of neutral, cationic and anionic polystyrene nanoparticles with cells from the human alveolar compartment: robust response of alveolar type 1 epithelial cells [PDF]

, 2015
BACKGROUND: Engineered nanoparticles (NP) are being developed for inhaled drug delivery. This route is non-invasive and the major target; alveolar epithelium provides a large surface area for drug administration and absorption, without first pass ...
Ruenraroengsak, P, Tetley, TD
core   +2 more sources

Solvent‐Free Bonding Mechanisms and Microstructure Engineering in Dry Electrode Technology for Lithium‐Ion Batteries

Advanced Functional Materials, EarlyView.
Dry electrode technology revolutionizes battery manufacturing by eliminating toxic solvents and energy‐intensive drying. This work details two promising techniques: dry spray deposition and polymer fibrillation. How their unique solvent‐free bonding mechanisms create uniform microstructures for thicker, denser electrodes, boosting energy density and ...
Yuhao Liang, Hao Long, Zimo Huang, Ting He, Xueming Chen, Meng Li, Hao Chen, Shanqing Zhang   +7 more
wiley   +1 more source

In Vitro Systems Toxicology Assessment of Nonflavored e-Cigarette Liquids in Primary Lung Epithelial Cells

, 2017
Electronic nicotine delivery systems (ENDS) dispense nicotine by heating a solution (e-liquid) and generating an aerosol that is then inhaled by the user. ENDS have been previously reported by some as less harmful than conventional cigarettes.
I. Gonzalez-Suarez, D. Marescotti, F. Martin, Elena Scotti, E. Guedj, S. Acali, Rémi H. J. Dulize, Karin Baumer, Dariusz Peric, S. Frentzel, N. Ivanov, J. Hoeng, M. Peitsch   +12 more
semanticscholar   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

A Network Toxicology Approach for Mechanistic Modelling of Nanomaterial Hazard and Adverse Outcomes

Advanced Science
Hazard assessment is the first step in evaluating the potential adverse effects of chemicals. Traditionally, toxicological assessment has focused on the exposure, overlooking the impact of the exposed system on the observed toxicity.
Giusy del Giudice, Angela Serra, Alisa Pavel, Marcella Torres Maia, Laura Aliisa Saarimäki, Michele Fratello, Antonio Federico, Harri Alenius, Bengt Fadeel, Dario Greco   +9 more
doaj   +1 more source

Mobile air quality studies (MAQS) in inner cities: particulate matter PM10 levels related to different vehicle driving modes and integration of data into a geographical information program [PDF]

, 2012
: BACKGROUND: Particulate matter (PM) is assumed to exert a major burden on public health. Most studies that address levels of PM use stationary measure systems.
Fischer, Axel, Groneberg, Jan David Alexander, Hoang, Diana My Linh, Klingelhöfer, Doris, Mueller, Daniel, Quarcoo, David, Scutaru, Cristian, Spallek, Michael, Takemura, Masaya, Uibel, Stefanie, Unger, Volker   +10 more
core   +2 more sources

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

Advanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li, Elliya Park, Chunsheng He, Azhar Z. Abbasi, Pei Zhi, Paul E. Fraser, Andrew M. Rauth, Jeffery T. Henderson, Xiao Yu Wu   +8 more
wiley   +1 more source

Isolation of a Stenotrophomonas strain and identification of methyltransferase genes conferring the high arsenic volatilizing ability

Applied and Environmental Microbiology
Microbial arsenic (As) volatilization plays a significant role in the global As biogeochemical cycle and presents a promising approach for bioremediation. In this study, an autotrophic strain of Stenotrophomonas maltophilia was isolated from sewage water
Diksha Singh, Nitish Sharma, Sheetal Agarwal, Sadaf Aiman Khan, Veena Jain, Sukhveer Singh, Somendu Roy, Kusum Yadav, Sudhir Pratap Singh, Vikas Srivastava   +9 more
doaj   +1 more source

The fate of steroid estrogens: Partitioning during wastewater treatment and onto river sediments [PDF]

, 2010
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2010 Springer Science+Business Media B.V.The partitioning of steroid estrogens in wastewater treatment and receiving waters is likely to ...
A Joss, A Soares, AC Johnson, AC Layton, AI Schafer, AM Robertson, AO Ifelebuegu, CE Purdom, CX Huo, Elise Cartmell, G-G Ying, JC Bowman, John N. Lester, KH Langford, KH Langford, KIE Holthaus, KM Lai, KM Lai, KM Lai, KM Lai, KU Goss, M Clara, M Hunter, M Trimmer, Mark D. Scrimshaw, MCB Braga, MD Scrimshaw, MD Scrimshaw, ND Bedding, NF Gray, OAH Jones, OAH Jones, OAH Jones, OV Martin, P Labadie, PH Dowson, PN Taylor, R Kanda, Rachel L. Gomes, RD Wauchope, RJ Williams, RL Gomes, RL Gomes, RL Gomes, RL Gomes, RP Schwarzenbach, RSK Buisson, S Jobling, S Stoveland, S Stoveland, S Stoveland, SB O’Reilly-Wiese, SB O’Reilly-Wiese, T Stephenson, TA Ternes, TY Chiu, YKK Koh, YKK Koh, YKK Koh   +58 more
core   +1 more source

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

Advanced Healthcare Materials, EarlyView.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk, JoAnn C. L. Schuh, Brad Bolon, Valerie S. Thomas, Jeffrey I. Everitt, Abraham Nyska, Jaime Paulin   +6 more
wiley   +1 more source