Results 11 to 20 of about 11,020,373 (290)
T-bet controls severity of hypersensitivity pneumonitis [PDF]
Journal of Inflammation, 2011 Hypersensitivity Pneumonitis (HP) is an interstitial lung disease that develops following repeated exposure to inhaled environmental antigens. The disease is characterized by alveolitis, granuloma formation and in some patients' fibrosis.
Nance Stephanie C +3 more
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T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex [PDF]
Cell Reports, 2016 The transcription factor T-bet directs Th1 cell differentiation, but the molecular mechanisms that underlie this lineage-specific gene regulation are not completely understood.
Arnulf Hertweck +13 more
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T-bet syndrome-associated bronchial asthma phenotype [PDF]
Медицинская иммунология, 2020 We aimed to evaluate a significance of T-bet transcription factor in bronchial asthma (BA). A total of 102 patients with BA were examined. The control group was represented by healthy subjects (21 people).
L. N. Sorokina +3 more
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The Diagnostic Value of Transcription Factors T-bet/GATA3 Ratio in Predicting Antibody-Mediated Rejection [PDF]
Clinical and Developmental Immunology, 2013 Background. Previous data showed that the predominance of intraglomerular T-bet or GATA3 is correlated with different mechanisms of rejection, suggesting that the ratio of T-bet/GATA3 might be used to distinguish antibody-mediated rejection (ABMR) and T ...
Xue Li +4 more
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"T-bet"-ing on autoimmunity variants. [PDF]
PLoS Genetics, 2017 Michelle L T Nguyen +2 more
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Nature Immunology, 2011 The activation of immune-defense mechanisms in response to a microbial attack must be robust and appropriately tailored to fight particular types of pathogens. Infection with intracellular microorganisms elicits a type 1 inflammatory response characterized by mobilization of T helper type 1 (T(H)1) cells to the site of infection, where they are ...
Vanja, Lazarevic, Laurie H, Glimcher
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T‐bet or not T‐bet: Taking the last bow on the autoimmunity stage [PDF]
European Journal of Immunology, 2013 The search for the encephalitogenic factor driving pathogenic T cells in autoimmune diseases such as rheumatoid arthritis, multiple sclerosis (MS), and psoriasis has proven to be a long and difficult mission, which is not yet completed. In this issue of the European Journal of Immunology, the importance of the transcription factor T‐bet, previously ...
Spath, Sabine, Becher, Burkhard
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Scientific Reports, 2021 T-bet is a key transcription factor for the T helper 1 lineage and its expression level is negatively correlated to inflammation in patients with rheumatoid arthritis (RA).
Masaru Shimizu +8 more
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Immunity, 2017 In this issue of Immunity, Iwata et al. (2017) report that the transcription factor T-bet acts as a selective repressor of the type I interferon (IFN) transcriptional program in response to IFN-γ signaling.
Vanja, Lazarevic +2 more
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Zdorovʹe Rebenka, 2023 Background. Breast milk (BM) is an optimal nutritional product for newborns and a source of exogenous microRNAs (miR). MiR-148a is one of the most highly expressed miR of BM. Currently, there is a lack of data on the miR-148a effect on the development of
O.E. Abaturov, A.O. Tovarnytska
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