Results 11 to 20 of about 10,355,186 (284)
T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex
Cell Reports, 2016 The transcription factor T-bet directs Th1 cell differentiation, but the molecular mechanisms that underlie this lineage-specific gene regulation are not completely understood.
Arnulf Hertweck +13 more
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T‐bet or not T‐bet: Taking the last bow on the autoimmunity stage [PDF]
European Journal of Immunology, 2013 The search for the encephalitogenic factor driving pathogenic T cells in autoimmune diseases such as rheumatoid arthritis, multiple sclerosis (MS), and psoriasis has proven to be a long and difficult mission, which is not yet completed. In this issue of the European Journal of Immunology, the importance of the transcription factor T‐bet, previously ...
Spath, Sabine, Becher, Burkhard
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Cell Metabolism, 2013 Although increasing adiposity is usually associated with adipose tissue infiltration by inflammatory cells and systemic insulin resistance, Stolarczyk et al. (2013) report in this issue that mice deficient in the T-box transcription factor, T-bet, display a dissociated phenotype with enhanced perigonadal adipose but enhanced insulin sensitivity.
Locksley, Richard M.
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T-bet syndrome-associated bronchial asthma phenotype [PDF]
Медицинская иммунология, 2020 We aimed to evaluate a significance of T-bet transcription factor in bronchial asthma (BA). A total of 102 patients with BA were examined. The control group was represented by healthy subjects (21 people).
L. N. Sorokina +3 more
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"T-bet"-ing on autoimmunity variants. [PDF]
PLoS Genetics, 2017 Michelle L T Nguyen +2 more
doaj +6 more sources
, 2019 9th Bet Debora Conference "Jewish Women: Being Present, Bringing Change" covered following topics: contemporary women’s perspectives on Jewish tradition; advocacy for other minority groups: activism against antisemitism, antiziganism, racism, and ...
core +7 more sources
Evaluation of IFN-γ and T-bet Expression Levels as Possible Molecular Markers of Schizophrenia [PDF]
Journal of Cell and Molecular Research, 2020 Schizophrenia is an irritating mental disorder that affects around 1% of the world's population. The immune system contributes to the onset of the disease, particularly through production and secretion of some cytokines.
Roghaye Lorestani +3 more
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Сучасна педіатрія: Україна, 2022 Некротизуючий ентероколіт (НЕК) - тяжке гастроінтестинальне захворювання, що уражує переважно недоношених немовлят. Неспецифічність клінічної картини та високий відсоток ускладнень обумовлюють необхідність ранньої діагностики та профілактики захворювання.
O.E. Abaturov, A.O. Tovarnytska
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Frontiers in Immunology, 2021 T-bet, a T-box family member, is a transcription factor essential for the differentiation of naive CD4+ T cells into Th1 cells that are involved in both innate and adaptive immune responses.
Hongfei Tian +8 more
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Nature Immunology, 2011 The activation of immune-defense mechanisms in response to a microbial attack must be robust and appropriately tailored to fight particular types of pathogens. Infection with intracellular microorganisms elicits a type 1 inflammatory response characterized by mobilization of T helper type 1 (T(H)1) cells to the site of infection, where they are ...
Vanja, Lazarevic, Laurie H, Glimcher
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