Three PtIV prodrugs MRP, DRP, and HRP are designed to induce pyroptosis in low GSDME‐expressing tumor cells via the Caspase‐3/GSDME pathway. By relaxing chromatin and reactivating GSDME, HRP can effectively induce pyroptosis, enhance pro‐inflammatory cytokine production, and exhibit potent antitumor effects.
Xinda Yang+10 more
wiley +1 more source
Retracted: Correlation between T-Lymphocyte Subsets, Regulatory T Cells, and Hepatic Fibrosis in Patients with Nonalcoholic Fatty Liver. [PDF]
And Alternative Medicine EC.
europepmc +1 more source
T LYMPHOCYTE SUBSETS AND NEUTROPHIL CHEMOTAXIS AND ADHERENCE IN HEMOPHILIA (H) AND ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS) [PDF]
J Lewis+4 more
openalex +1 more source
This study identifies the RUNX1/SLAMF3 axis as a key driver of colorectal cancer liver metastasis (CRLM). SLAMF3 suppresses macrophage phagocytosis and depletes C1QC⁺ tumor‐associated macrophages, promoting an immunosuppressive microenvironment. Targeting this axis restores macrophage and CD8⁺ T cell activity and reduces metastasis.
Yinheng Luo+10 more
wiley +1 more source
Impact of Induction Immunosuppressants on T Lymphocyte Subsets after Kidney Transplantation: A Prospective Observational Study with Focus on Anti-Thymocyte Globulin and Basiliximab Induction Therapies. [PDF]
Kim HD+7 more
europepmc +1 more source
CD4+T-lymphocyte subsets in nonobese children with obstructive sleep apnea syndrome
Jin Ye+6 more
semanticscholar +1 more source
Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail+5 more
wiley +1 more source
Study on the correlation and clinical significance of T-lymphocyte Subsets, IL-6 and PCT in the severity of patients with sepsis. [PDF]
Li Q, Yan W, Liu S, Li H.
europepmc +1 more source
T LYMPHOCYTE SUBSETS IN CHILDREN WITH GRAM NEGATIVE SEPSIS [PDF]
Lakshmi D. Pappu+3 more
openalex +1 more source