Results 241 to 250 of about 344,235 (297)

The dysregulation of the immune microenvironment during endometrial intraepithelial neoplasia serves as a marker of endometrial carcinogenesis. [PDF]

Front Immunol
Peng Y, Zhong G, Zhou M, Yao Y, Dong K, Yang Z, An L, Zhang J, Zhang J, Zhang S, Tang Q, Wang H.   +11 more
europepmc   +1 more source

The enhanced cancer nanovaccine by bidirectionally blocking CXCL12/CXCR4 axis to inhibit the recurrence and metastasis of triple-negative breast cancer. [PDF]

Mol Cancer
Liu M, Ye W, Ji Q, Zhang B, Yang Z, Liu D, Zhou S.   +6 more
europepmc   +1 more source

Cytomegalovirus Drives the Development of Cytotoxic CD4⁺ T Cells in Patients With Multiple Sclerosis. [PDF]

Neurol Neuroimmunol Neuroinflamm
Hoeks C, Boeckx B, Baeten P, Hermans D, Randall J, Van Wijmeersch B, Popescu V, Somers V, Stinissen P, Lambrechts D, Broux B, Hellings N.   +11 more
europepmc   +1 more source

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Cytotoxic T-lymphocytes.

Advances in internal medicine, 1988
Cytotoxic T-lymphocytes have received intensive scrutiny in the past decade, and have been implicated as important effector cells in diverse clinical settings. A variety of technological advances--the establishment of T cell clones, the production of MAb, the production of pure lymphokines through gene cloning, the modification of target cells by gene ...
S, Martin, E, Cantin, B T, Rouse
openaire   +4 more sources

Suppressor‐Cytotoxic T‐Lymphocyte Panniculitis

Pediatric Dermatology, 1986
Abstract: A 3½‐year‐old girl had fever and nonsuppurative panniculitis. Biopsies revealed lobular lymphocytic panniculitis. An extensive evaluation of the patient for infectious and other systemic diseases yielded negative results. Although the number of peripheral T lymphocytes was normal, suppressor‐cytotoxic (0KT8) lymphocytes predominated in the ...
A R, Solomon, A G, Kantak, J E, Ramirez, S, Rajaraman, S S, Raimer, A S, Goldman   +5 more
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Endocytosis in cytotoxic T-lymphocytes

Cellular Immunology, 1981
Abstract Endocytosis in T lymphocytes was analyzed during their differentiation into cytotoxic effector cells in allogeneic mixed lymphocyte cultures. We found that endocytic activity increases from a very low value to reach a peak at Day 5, at which time the cytotoxic titer is highest in these cell cultures.
Heiniger, H J, Sodergren, A, Marshall, J D   +2 more
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Cytotoxic T lymphocytes against HIV

AIDS, 1990
HIV-1 infection has clearly been shown to induce a vigorous CTL response in infected people, and this response is present at a time when immune function otherwise is globally impaired. HIV-1-specific CTL are detectable both in peripheral blood and tissues of infected people, and are aimed at multiple viral proteins.
B D, Walker, F, Plata
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T lymphocytes with promiscuous cytotoxicity

Nature, 1976
CYTOTOXIC T lymphocytes generated during a unidirectional mixed lymphocyte culture (MLC) lyse target cells which have the antigenic phenotype of the allogeneic stimulating cells. The cytotoxic effect is restricted to cells that bear the same major histocompatibility antigens (H–2 antigens in mice) as the stimulating cells1.
C, Shustik, I R, Cohen, R S, Schwartz, E, Latham-Griffin, S D, Waksal   +4 more
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Cytotoxic T lymphocytes and autoimmunity

Current Opinion in Rheumatology, 2005
The possibility of the recognition by cytotoxic T lymphocytes of tissue autoantigens has been largely ignored in explaining organ-specific autoimmune diseases. Recent advances in the understanding of human leukocyte antigen class I-binding peptides motifs have led to the detection and the characterization of those autoreactive CD8(+) cytotoxic T ...
Patrick, Blanco, Jean-François, Viallard, Jean-Luc, Pellegrin, Jean-François, Moreau   +3 more
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Human Cytotoxic T Lymphocytes

Scandinavian Journal of Immunology, 1985
A limiting‐dilution system was established to measure the frequency of alloreactive cytotoxic T‐lymphocyte precursors (CTL‐p) in human peripheral blood T cells. Culture medium supple mented with recombinant interleukin‐2 enabled clonal expansion of all CTL‐p stimulated by allogeneic peripheral blood or spleen cells.
D, Kabelitz, W R, Herzog, B, Zanker, H, Wagner   +3 more
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