Results 251 to 260 of about 271,681 (306)
Some of the next articles are maybe not open access.
Annals of the New York Academy of Sciences, 1988
We have used recombinant vaccinia viruses expressing the cloned genes coding for glycoprotein B (gB) or glycoprotein D (gD) of HSV-1 to analyze the role of HSV-1--specific cytotoxic T lymphocytes (CTL) in antiviral immunity. Various studies in mice revealed that either vector could stimulate some aspects of HSV-1--specific immunity, but surprisingly ...
S, Martin, E, Cantin, B T, Rouse
openaire +4 more sources
We have used recombinant vaccinia viruses expressing the cloned genes coding for glycoprotein B (gB) or glycoprotein D (gD) of HSV-1 to analyze the role of HSV-1--specific cytotoxic T lymphocytes (CTL) in antiviral immunity. Various studies in mice revealed that either vector could stimulate some aspects of HSV-1--specific immunity, but surprisingly ...
S, Martin, E, Cantin, B T, Rouse
openaire +4 more sources
Endocytosis in cytotoxic T-lymphocytes
Cellular Immunology, 1981Abstract Endocytosis in T lymphocytes was analyzed during their differentiation into cytotoxic effector cells in allogeneic mixed lymphocyte cultures. We found that endocytic activity increases from a very low value to reach a peak at Day 5, at which time the cytotoxic titer is highest in these cell cultures.
Heiniger, H J +2 more
openaire +2 more sources
T lymphocytes with promiscuous cytotoxicity
Nature, 1976CYTOTOXIC T lymphocytes generated during a unidirectional mixed lymphocyte culture (MLC) lyse target cells which have the antigenic phenotype of the allogeneic stimulating cells. The cytotoxic effect is restricted to cells that bear the same major histocompatibility antigens (H–2 antigens in mice) as the stimulating cells1.
C, Shustik +4 more
openaire +2 more sources
Cytotoxic T lymphocytes and autoimmunity
Current Opinion in Rheumatology, 2005The possibility of the recognition by cytotoxic T lymphocytes of tissue autoantigens has been largely ignored in explaining organ-specific autoimmune diseases. Recent advances in the understanding of human leukocyte antigen class I-binding peptides motifs have led to the detection and the characterization of those autoreactive CD8(+) cytotoxic T ...
Patrick, Blanco +3 more
openaire +2 more sources
The lysis of cytotoxic T lymphocytes and their blasts by cytotoxic T lymphocytes.
Immunology, 1991After binding to their targets, cytotoxic T lymphocytes (CTL) deliver a lethal hit signal, ultimately leading to target cell lysis, and then can recycle to lyse additional targets, without themselves being destroyed. If non-specific secreted lytic mediators are involved in such lysis.
B, Schick, G, Berke
openaire +1 more source
The stepwise activation of cytotoxic T lymphocytes
Immunology Today, 1987The recognition of antigen is the first stage of T-lymphocyte maturation in vivo. Monoclonal antibodies directed against the T-cell receptor/CD3 complex and against other surface antigens can also provide this stimulus. Gianni Gromo and his colleagues are attempting to characterize the steps leading from this initial activation to full functional ...
G, Gromo +4 more
openaire +2 more sources