Results 251 to 260 of about 564,677 (319)

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

Immune microenvironment and immunotherapy in hepatocellular carcinoma: mechanisms and advances. [PDF]

Front Immunol
Xie D, Liu Y, Xu F, Dang Z, Li M, Zhang Q, Dang Z.   +6 more
europepmc   +1 more source

Pyroptosis‐Inducing Platinum(IV) Prodrugs via GSDME Pathway for Chemoimmunotherapy and Metastasis Inhibition in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Three PtIV prodrugs MRP, DRP, and HRP are designed to induce pyroptosis in low GSDME‐expressing tumor cells via the Caspase‐3/GSDME pathway. By relaxing chromatin and reactivating GSDME, HRP can effectively induce pyroptosis, enhance pro‐inflammatory cytokine production, and exhibit potent antitumor effects.
Xinda Yang, Chuansheng Xu, Youliang Zeng, Chunhui Wang, Yan Gao, Jie Ding, Sirui Chen, Yuheng Pan, Xin Zhang, Zongwan Mao, Shuo Shi   +10 more
wiley   +1 more source

Functional T cell response to COVID-19 vaccination with or without natural infection with SARS-CoV-2 in adults and children. [PDF]

Sci Rep
Akhtar E, Kuddusi RU, Talukder MT, Jakarea M, Haq MA, Hossain MS, Vandenent M, Islam MZ, Zaman RU, Razzaque A, Sarker P, Raqib R.   +11 more
europepmc   +1 more source

Prognostic impact of postoperative fixed‐point inflammation in patients with gastric cancer after curative gastrectomy: A validation cohort study

Annals of Gastroenterological Surgery, EarlyView.
The cutoff value of CRP by sex for poor OS remains unclear. This study aimed to determine the cutoff values of CRP on postoperative day 3 to predict poor OS in men and women with gastric cancer after radical gastrectomy. The high‐CRP group has poorer overall survival than the low‐CRP group for gastric cancer after gastrectomy.
Ryota Matsui, Manabu Ohashi, Motonari Ri, Rie Makuuchi, Tomoyuki Irino, Masaru Hayami, Takeshi Sano, Souya Nunobe   +7 more
wiley   +1 more source

Designing a multi-epitope vaccine against African swine fever virus using immunoinformatics approach. [PDF]

Sci Rep
Venkateswaran D, Prakash A, Nguyen QA, Suntisukwattana R, Atthaapa W, Tantituvanont A, Nilubol D.   +6 more
europepmc   +1 more source

Near‐Infrared Organic Room Temperature Phosphorescent Probes Targeting Fibroblast Activation Protein for Surgical Navigation of Liver Cancer

Aggregate, EarlyView.
A near‐infrared organic room temperature phosphorescence probe of fibroblast‐activation protein in liver cancer microenvironment is prepared to accurately locate liver cancer and determine surgical margins, aiming at guiding hepatectomy and achieving accurate liver cancer resection.
Jinghua Li, Juqing Gu, Liangxuan Ding, Xiaomian Li, Peng Xia, Fusheng Liu, Xi Chen, Weijie Ma, Yong He, Qianqian Li, Zhen Li, Yufeng Yuan   +11 more
wiley   +1 more source

CD4⁺T and CD8⁺T cells profile in lung inflammation and fibrosis: targets and potential therapeutic drugs. [PDF]

Front Immunol
Sun X, Zhang X, He Y, Du X, Cai Q, Liu Z.   +5 more
europepmc   +1 more source

Hydrogel‐Based Smart Materials for Wound Healing and Sensing

Aggregate, EarlyView.
The graphical abstract illustrates the role of hydrogel‐based flexible materials in advancing biomedical applications, including wound healing, point‐of‐care diagnostics, smart patches, and wearable devices. Hydrogels are particularly promising in modern wound care due to their high‐water content, flexibility, and biocompatibility.
Thi Kim Ngan Duong, Thi Thuy Truong, Thi Nhat Linh Phan, Thi Xuan Nguyen, Vu Hoang Minh Doan, Truong Tien Vo, Jaeyeop Choi, Umapada Pal, Prodyut Dhar, Byeongil Lee, Junghwan Oh, Sudip Mondal   +11 more
wiley   +1 more source

Inflammation, Immunosuppression, and Immunotherapy in Pancreatic Cancer-Where Are We Now? [PDF]

Cancers (Basel)
Fudalej M, Krupa K, Badowska-Kozakiewicz A, Deptała A.   +3 more
europepmc   +1 more source