Results 291 to 300 of about 564,677 (319)

CD4 cytotoxic T lymphocyte differentiation

Biochimie, 1988
In vitro allostimulated CD4+ human lymphocytes were cloned by micromanipulation and expanded for a short time in IL-2 conditioned medium. In the present study we observed that proliferative noncytotoxic cloned cells were able to acquire the specific cytolytic activity under some modification of the cloned cells restimulation cycle. We demonstrated that
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Cytotoxic CD8+ Lymphocytes in the Tumor Microenvironment.

Advances in Experimental Medicine and Biology, 2020
K. Iwahori
semanticscholar   +1 more source

THE MECHANISM OF LYMPHOCYTE‐MEDIATED CYTOTOXICITY

Biological Reviews, 1981
Summary1. Three classes of cytotoxic lymphocyte are discussed: thymus‐derived T cells, antibody‐dependent K cells and NK (natural killer) cells. Each of these cytotoxic lymphocytes has receptors allowing the formation of adhesions (contact) with a target cell (the cell to be killed).
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Radiosensitivity of Murine T-Lymphocyte Cytotoxicity

Radiation Research, 1984
A biphasic curve was observed when surviving allogeneic lytic activity was plotted as a function of irradiation delivered before sensitization. Flow cytometry analysis demonstrated that the number of cells was reduced in response to increasing dose and that subset precursors Lyt 1+2+ were proportionally more radiosensitive than the other subsets ...
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T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

Nature, 1998
S. Schoenberger, R. Toes, E. V. D. Voort, R. Offringa, C. Melief   +4 more
semanticscholar   +1 more source

Apoptosis and Cytotoxic T Lymphocytes

1993
Apoptosis is a mode of cell death that occurs under normal physiological conditions. In vivo, it is most often found during normal tissue turnover, embryogenesis, metamorphosis, and endocrine-dependent tissue atrophy (Kerr et al., 1972; Wyllie et al., 1980). The inference has been made that cell death in these instances is “programmed,” meaning that it
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Cytotoxic lymphocytes for the clinic

Cytotherapy, 2006
Austin John Barrett, John G Sharp
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The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides

Cell, 1986
A. Townsend, J. Rothbard, F. Gotch, G. Bahadur, D. Wraith, A. McMichael   +5 more
semanticscholar   +1 more source

Antiviral pressure exerted by HIV-l-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

Nature Network Boston, 1997
P. Borrow, H. Lewicki, Xiping Wei, M. Horwitz, N. Peffer, Heather L. Meyers, J. Nelson, J. Gairin, B. Hahn, M. Oldstone, G. Shaw   +10 more
semanticscholar   +1 more source

Lymphocyte-mediated Cytotoxicity

Pediatric Annals, 1987
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