Results 41 to 50 of about 310,158 (300)
Immune networks: multi-tasking capabilities near saturation [PDF]
Journal of Physics A 46, 415003 (2013). (IOP Select:
Highlights-2013), 2013 Pattern-diluted associative networks were introduced recently as models for the immune system, with nodes representing T-lymphocytes and stored patterns representing signalling protocols between T- and B-lymphocytes. It was shown earlier that in the regime of extreme pattern dilution, a system with $N_T$ T-lymphocytes can manage a number $N_B!=!\order ...
arxiv +1 more source
Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma [PDF]
, 2000 Immune surveillance by cytotoxic lymphocytes against cancer has been postulated for decades, but direct evidence for the role of cytotoxic lymphocytes in protecting against spontaneous malignancy has been lacking.
Godfrey, DI +5 more
core +2 more sources
Phytochemical study and evaluation of the cytotoxic properties of methanolic extract from Baccharis obtusifolia [PDF]
International Journal of Medicinal Chemistry, 2018, 2019 Some species of the Baccharis genus have been shown to possess important biomedical properties, including cytotoxic activity. In this study, we examined the cytotoxic effect of methanol extract from Baccharis obtusifolia (Asteraceae) in cancer cell lines of prostate (PC-3), colon (RKO), astrocytoma (D-384), and breast (MCF-7).
arxiv +1 more source
Immunobiology, 1984 The phenotype of lymphocytes, obtained from mice immunized with allogeneic tumor cells, with the capacity to induce macrophage cytotoxicity was determined. Macrophage cytotoxicity was induced, either by incubating the macrophages with Macrophage Arming Factor (MAF) containing supernatants of cultures of sensitized lymphocytes and tumor cells (arming ...
E Pels, W. Den Otter, R.A. de Weger
openaire +3 more sources
State of the immune system in women using the “Provag” probiotic
Медицинская иммунология, 2020 Lactobacilli are widely used in clinical practice as probiotics, biologically active additives and probiotic products for functional nutrition.
V. A. Kozlov +4 more
doaj +1 more source
Enhanced CXCR4 Expression of Human CD8Low T Lymphocytes Is Driven by S1P4
Frontiers in Immunology, 2021 Although the human immune response to cancer is naturally potent, it can be severely disrupted as a result of an immunosuppressive tumor microenvironment.
Tobias Burkard +6 more
doaj +1 more source
Estimation of In-Vitro Free Radical Scavenging and Cytotoxic Activities of Thiocarbohydrazones Derivatives [PDF]
arXiv, 2023 Objective: To investigate free radical scavenging potential of thiocarbohydrazones derivatives for the discovery of antioxidant compounds of synthetic origin. Method: Eighteen thiocarbohydrazones derivatives were screened for antioxidant activities by using in vitro radical inhibition assay.
arxiv
Spatiotemporal dynamics of a glioma immune interaction model
Scientific Reports, 2021 We report a mathematical model which depicts the spatiotemporal dynamics of glioma cells, macrophages, cytotoxic-T-lymphocytes, immuno-suppressive cytokine TGF-β and immuno-stimulatory cytokine IFN-γ through a system of five coupled reaction-diffusion ...
Subhas Khajanchi, Juan J. Nieto
doaj +1 more source
CD39 molecule: a negative regulator expressed on T cells in patients with lung adenocarcinoma
Archives of Medical Science, 2023 Introduction The function of cytotoxic cells may be impacted by CD39 expression on CD8-positive T lymphocytes, leading to an imbalance in tumor immunity.
Lu Tang, Hao Jin
doaj +1 more source
Abnormal distribution of CD8 subpopulation in B-chronic lymphocytic leukemia identified by flow cytometry [PDF]
, 1988 We studied the occurrence of T-cell subpopulations for patients with B-cell chronic lymphocytic leukemia. The CD8+ population was divided into CD8+ suppressor (CD8a+) and CD8+ cytotoxic (CD8b+) lymphocytes using difference in orthogonal light scattering.\
B.G.De Grooth +30 more
core +2 more sources