Results 31 to 40 of about 8,441,406 (356)
Cells within cells (within cells) [PDF]
The Journal of Cell Biology, 2007 ![][1] Within 6 hours of detachment from their substrate, one cell becomes entirely enclosed by another. BRUGGE/ELSEVIER One tumor cell can burrow its way entirely inside another.
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Destabilizing the autoinhibitory conformation of Zap70 induces up-regulation of inhibitory receptors and T cell unresponsiveness. [PDF]
, 2017 Zap70 plays a critical role in normal T cell development and T cell function. However, little is known about how perturbation of allosteric autoinhibitory mechanisms in Zap70 impacts T cell biology.
Chen, Yiling +4 more
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ATOPIC DERMATITIS: FROM MOLECULAR SPECIFICITY OF ORAL MANIFESTATIONS TO CLINICAL IMPLICATIONS
Romanian Journal of Oral Rehabilitation, 2022 Atopic dermatitis (AD) is considered a systemic disease that also manifests itself in the oral cavity. The presence of oral pathologies in patients with atopic dermatitis can result in the worsening of the atopic disease, and on the other hand, the ...
Petronela Bărgăoanu +4 more
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Cell–cell and cell–matrix interactions
Molecular Biology of the Cell, 2012 Cell–cell and cell–extracellular matrix (ECM) interactions are fundamental to the complexity of multicellularity achieved in the metazoa. These interactions share many conceptual similarities, the most prominent being a dependence on transmembrane adhesion receptors, binding of adhesion receptors to specific extracellular ligand partners, and the ...
Josephine C. Adams, Kris A. DeMali
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Romanian Journal of Oral Rehabilitation, 2021 Aim of the study The current pandemic context, with a significant negative impact on the oral mucosa pathology, requires intensified research on the risk of malignant transformation of the most common premalignant oral lesions, precursors of oral ...
Doinița Temelie-Olinici +7 more
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Peptide Super-Agonist Enhances T-Cell Responses to Melanoma
Frontiers in Immunology, 2019 Recent immunotherapeutic approaches using adoptive cell therapy, or checkpoint blockade, have demonstrated the powerful anti-cancer potential of CD8 cytotoxic T-lymphocytes (CTL).
Sarah A. E. Galloway +18 more
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Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse
Nature Communications, 2019 The immune synapse at the interface between T cells and antigen-presenting cells manifests intense vesicular trafficking, but how the vesicles are sorted is still unclear.
Andres Ernesto Zucchetti +10 more
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OncoImmunologyThere has been growing interest in the role of B cells in antitumour immunity and potential use in adoptive cellular therapies. To date, the success of such therapies is limited.
Thomas V. Guy +4 more
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Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy [PDF]
, 2020 Chimeric antigen receptor (CAR) T-cell therapy has produced remarkable anti-tumor responses in patients with B-cell malignancies. However, clonal kinetics and transcriptional programs that regulate the fate of CAR-T cells after infusion remain poorly ...
Adair, Jennifer E. +16 more
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Cell–cell and cell–matrix interactions
Molecular Biology of the Cell, 2014 mbc.E13-11-0671 Molecular Biology of the Cell Volume 25 Page 731 MBoC is pleased to publish this summary of the Minisymposium “Cell−Cell/Cell−Matrix Interactions and Intracellular Signaling” held at the American Society for Cell Biology 2013 Annual Meeting, New Orleans, LA, December 15, 2013.
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