Results 31 to 40 of about 8,006,579 (361)
CD137: A Member of the TNFR Family - in Psoriasis Skin Lesions in Comparison with Normal Skin Specimens [PDF]
Iranian Journal of Pathology, 2021 Background and Objective: CD137 is a member of the TNF-Receptor family. TNF-alpha antagonists have therapeutic effect in active psoriasis. In this study, the relative frequency of CD137 expression was investigated in the inflammatory cells of psoriasis ...
Parvin Rajabi +3 more
doaj +1 more source
Destabilizing the autoinhibitory conformation of Zap70 induces up-regulation of inhibitory receptors and T cell unresponsiveness. [PDF]
, 2017 Zap70 plays a critical role in normal T cell development and T cell function. However, little is known about how perturbation of allosteric autoinhibitory mechanisms in Zap70 impacts T cell biology.
Chen, Yiling +4 more
core +2 more sources
Cell-in-cell: A virgin land of cell biology [PDF]
OncoImmunology, 2013 Cell-in-cell affects multiple functions of both internalized and internalizing cells. Immune effector cells and their targets can also interact in this fashion. We have recently investigated the outcome of cell-in-cell, the molecular mechanisms underpinning this phenomenon, and its relevance in both physiological and pathological conditions.
Ying Wang, Xiaoning Wang
openaire +3 more sources
ATOPIC DERMATITIS: FROM MOLECULAR SPECIFICITY OF ORAL MANIFESTATIONS TO CLINICAL IMPLICATIONS
Romanian Journal of Oral Rehabilitation, 2022 Atopic dermatitis (AD) is considered a systemic disease that also manifests itself in the oral cavity. The presence of oral pathologies in patients with atopic dermatitis can result in the worsening of the atopic disease, and on the other hand, the ...
Petronela Bărgăoanu +4 more
doaj
International Journal of Hyperthermia, 2021 Background This study aimed to evaluate whether combined therapy with PD-1 blockade (anti-PD-1) and radiofrequency ablation (RFA) is superior to RFA monotherapy for recurrent hepatocellular carcinoma (HCC).
Xiaofei Wang +7 more
doaj +1 more source
Human natural killer cell committed thymocytes and their relation to the T cell lineage. [PDF]
, 1993 Recent studies have demonstrated that mature natural killer (NK) cells can be grown from human triple negative (TN; CD3-, CD4-, CD8-) thymocytes, suggesting that a common NK/T cell precursor exists within the thymus that can give rise to both NK cells ...
Lanier, LL +3 more
core +1 more source
Cells within cells (within cells) [PDF]
The Journal of Cell Biology, 2007 ![][1] Within 6 hours of detachment from their substrate, one cell becomes entirely enclosed by another. BRUGGE/ELSEVIER One tumor cell can burrow its way entirely inside another.
openaire +2 more sources
Romanian Journal of Oral Rehabilitation, 2021 Aim of the study The current pandemic context, with a significant negative impact on the oral mucosa pathology, requires intensified research on the risk of malignant transformation of the most common premalignant oral lesions, precursors of oral ...
Doinița Temelie-Olinici +7 more
doaj
Peptide Super-Agonist Enhances T-Cell Responses to Melanoma
Frontiers in Immunology, 2019 Recent immunotherapeutic approaches using adoptive cell therapy, or checkpoint blockade, have demonstrated the powerful anti-cancer potential of CD8 cytotoxic T-lymphocytes (CTL).
Sarah A. E. Galloway +18 more
doaj +1 more source
OncoImmunology, 2021 Based on the success of tumor-infiltrating lymphocytes (TIL)-based therapies, personalized adoptive cell therapies (ACT) targeting neoantigens have the potential to become a disruptive technology and lead to highly effective treatments for cancer ...
Florian Kast +4 more
doaj +1 more source