Results 171 to 180 of about 95,123 (301)

Corrigendum to Co-receptor CD8-mediated modulation of T-cell receptor functional sensitivity and epitope recognition degeneracy

Frontiers in Immunology, 2014
Hugo Antonius Van Den Berg
doaj   +1 more source

Distinct characteristics of T cell receptor repertoire associated with the SARS-CoV-2 reinfection. [PDF]

Front Immunol
Zeng L, Liu L, Ren B, Feng B, Lai X, Lai X, Chen Z, Huang Y, Hong W.   +8 more
europepmc   +1 more source

Influence of randomness in mathematical models for diffraction and T-cell recognition

, 2009
Zint N. Influence of randomness in mathematical models for diffraction and T-cell recognition. Bielefeld (Germany): Bielefeld University; 2009.Stochastic models play an important part in many fields of science like physics and biology. In this thesis the
Zint, Natali
core  

Single‐Cell Level Characterization of B Cell Depletion and Repopulation Following Rituximab in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang, Norzawani Buang, Catherine Sutherland, Wanseon Lee, Lauren Overend, Tarran S. Rupall, Katie L. Burnham, Matthew C. Pickering, Marina Botto, Emma E. Davenport   +9 more
wiley   +1 more source

Anti‐Carbamylated Protein Antibodies Stabilize Carbamylated Histone H3 to Promote Synovial Activation and Neutrophil Extracellular Trap‐Mediated Bone Loss in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo, Norio Hanata, Eduardo Patino‐Martinez, Ronald Holewinski, Ana Barrera‐Vargas, Javier Merayo‐Chalico, Scott A. Coonrod, David A. Fox, Mariana J. Kaplan, Carmelo Carmona‐Rivera   +9 more
wiley   +1 more source

SatTCR: a pipeline for performing saturation analysis of the T cell receptor repertoire and a case study of a healthy canine. [PDF]

MethodsX
Welch Schwartz R, Zuleger CL, Newton MA, Vail DM, Albertini MR, Ong IM.   +5 more
europepmc   +1 more source

T Cell Plasticity in Systemic Lupus Erythematosus Revealed by Large‐Scale T Cell Receptor Repertoire and Transcriptome Studies

Arthritis &Rheumatology, EarlyView.
Objective We aimed to characterize CD4+ T cell plasticity in human systemic lupus erythematosus (SLE) by leveraging T cell receptor (TCR) repertoire features as markers of prior lineage states, integrating TCR and transcriptomic profiling to delineate plasticity patterns and evaluate their association with clinical disease activity. Methods We used TCR
Yasuo Nagafuchi, Masahiro Nakano, Kaitlyn A. Lagattuta, Mineto Ota, Hiroaki Hatano, Haruka Takahashi, Takahiro Itamiya, Hajime Inokuchi, Soumya Raychaudhuri, Tomohisa Okamura, Keishi Fujio, Kazuyoshi Ishigaki   +11 more
wiley   +1 more source

A fingerprint approach to pioneer structure-based T cell receptor repertoire analysis and specificity prediction. [PDF]

Front Immunol
Mayol-Rullan F, Bugnon M, Perez MAS, Zoete V.   +3 more
europepmc   +1 more source

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Tissue and peripheral T cell receptor repertoire predicts immunotherapy response and progression-free survival in NSCLC patients. [PDF]

Sci Rep
Pino-González M, Lázaro-Quintela M, Alonso-Álvarez I, Gallardo-Gómez M, Juaneda-Magdalena L, Francisco-Fernández A, Calabuig-Fariñas S, Jantus-Lewintre E, Martínez-Fernández M.   +8 more
europepmc   +1 more source