Results 191 to 200 of about 95,123 (301)

Comment on 'rigorous benchmarking of T cell receptor repertoire profiling methods for cancer RNA sequencing'. [PDF]

Brief Bioinform, 2023
Davydov AN, Bolotin DA, Poslavsky SV, Chudakov DM.   +3 more
europepmc   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Predictive potential of patient-specific immunological characteristics in solid cancers: circulating monocytes, myeloid-derived suppressor cells, T cells, and the T-cell receptor repertoire. [PDF]

ESMO Open
Zierfuss C, Niederdorfer B, Fendl B, Syböck K, Schedl J, Kohl L, Heller G, Tomasich E, Berger JM, Sunder-Plassmann V, Kleinberger M, Gottmann L, Korpan M, Starzer AM, Solano Henao I, Fürst J, Wolfsberg J, Grohmannova M, Dobrovits N, Ay C, Vladic N, Furtner J, Preusser M, Berghoff AS.   +23 more
europepmc   +1 more source

Mimic, target, and adapt: Cell membrane‐coated nanoplatforms for precision and immune‐guided cancer treatment

BMEMat, EarlyView.
This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam, Xiaojun Cai, Malik Ihsan Ullah Khan, Robert Musiol, Quazi T. H. Shubhra   +4 more
wiley   +1 more source

Investigating Early Kinetics in Plasma ctDNA and Peripheral T-cell Receptor Repertoire to Predict Treatment Outcomes to PD-1 Inhibitors in Head and Neck Squamous Cell Carcinoma. [PDF]

Clin Cancer Res
Sanz-Garcia E, Soleimani S, Bruce JP, Pedersen S, Tang M, Avery L, Eagles J, Spreafico A, Hansen AR, Eng L, Laliotis G, Krainock M, Liu M, Basra P, Yu C, Felicen S, Ohashi PS, Bratman SV, Pugh TJ, Siu LL.   +19 more
europepmc   +1 more source

T-Cell Receptor Repertoire as a Predictor of Immune-Related Adverse Events in Renal Cell Carcinoma. [PDF]

Curr Issues Mol Biol, 2023
Kobayashi T, Nagata M, Ikehata Y, Nagashima Y, Nagaya N, Lu Y, Horie S.   +6 more
europepmc   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Defining the genetic determinants of CD8⁺ T cell receptor repertoire in the context of immune checkpoint blockade. [PDF]

Sci Adv
Ng ES, Milotay G, Tong O, A Taylor C, Sun S, Niu G, Watson R, Sun B, MacKay S, Gilchrist JJ, Little M, Fairfax BP, Luo Y.   +12 more
europepmc   +1 more source

Individualised niches: an integrative conceptual framework across behaviour, ecology, and evolution

Biological Reviews, EarlyView.
ABSTRACT Individuals differ. While seemingly trivial, this insight has nevertheless led to paradigm shifts, as three key fields of organismal biology have seen marked changes in key concepts over the past few decades. In animal behaviour, it has become increasingly recognised that behavioural differences among individuals can be stable over time and ...
Oliver Krüger, Jaime Anaya‐Rojas, Mitja Back, Barbara Caspers, Nayden Chakarov, Melanie Dammhahn, Alkistis Elliott‐Graves, Claudia Fricke, Jürgen Gadau, Joseph I. Hoffman, Marie I. Kaiser, Sylvia Kaiser, Peter Korsten, Ulrich Krohs, Joachim Kurtz, Roland Langrock, Caroline Müller, Robert Peuß, Klaus Reinhold, Helene Richter, Norbert Sachser, Holger Schielzeth, Tim Schmoll, Ralf Stanewsky, Tamas Szekely, Franz J. Weissing, Meike Wittmann, Shuqing Xu   +27 more
wiley   +1 more source

Mice with a diverse human T cell receptor repertoire selected on multiple HLA class I molecules. [PDF]

Nat Commun
Dhamodaran A, Chen X, Fellmer N, Agrawal D, Danner E, Kühn R, Blankenstein T.   +6 more
europepmc   +1 more source