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CD4<sup>+</sup> T cells facilitate the RT-induced abscopal effect by promoting antigen cross-presentation to CD8<sup>+</sup> T cells at unirradiated tumor sites. [PDF]
Rao X +11 more
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Correction: Contribution of IL-17-producing γδ T cells to the efficacy of anticancer chemotherapy. [PDF]
Ma Y +21 more
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Ubiquitin E3 ligase KLHL6 brings exhausted T-cells back into action. [PDF]
Chen Z, Bullock AN, Kessler BM.
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2020
In 1891, Dr. William B. Coley, an American surgeon, made a compelling observation that immune system can be triggered to shrink tumors. The quest to exploit the power of immunotherapy however was forestalled by an era of chemotherapy that ensued.
Ranjit, Nair, Jason, Westin
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In 1891, Dr. William B. Coley, an American surgeon, made a compelling observation that immune system can be triggered to shrink tumors. The quest to exploit the power of immunotherapy however was forestalled by an era of chemotherapy that ensued.
Ranjit, Nair, Jason, Westin
openaire +3 more sources
T-cell therapies for T-cell lymphoma
Cytotherapy, 2019T-cell lymphomas represent a subpopulation of non-Hodgkin lymphomas with poor outcomes when treated with conventional chemotherapy. A variety of novel agents have been introduced as new treatment strategies either as first-line treatment or in conjunction with chemotherapy. Immunotherapy has been demonstrated to be a promising area for new therapeutics,
Keri Toner +2 more
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T Cell Receptors and T Cell Development
1996Birds provide a valuable model system for the study of early development. Studies of immune system development and function in chickens have contributed to some of the central tenets in immunology. These include:(1) allorecognition by lymphocytes in graft-vs-host (GVH) reactions (Simonsen 1985), (2) clonal reactivity of immunocompetent lymphocytes ...
C H, Chen +6 more
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