Results 41 to 50 of about 7,102,622 (207)

DR-bearing T lymphocytes in thoracic duct lymph [PDF]

open access: yes, 1981
T cells having DR antigens were shown to be present in high numbers in the thoracic duct lymph of patients undergoing long-term drainage. As drainage progresses the proportion of T DR cells in the lymph increases to levels as high as 70% at 6 weeks ...
Abo   +25 more
core   +1 more source

Fatty acids – from energy substrates to key regulators of cell survival, proliferation and effector function

open access: yesCell Stress, 2019
Recent advances in immunology and cancer research show that fatty acids, their metabolism and their sensing have a crucial role in the biology of many different cell types.
Danilo Cucchi   +5 more
doaj   +1 more source

Positive selection determines T cell receptor V beta 14 gene usage by CD8+ T cells. [PDF]

open access: yes, 1989
We report here a mAb, 14-2, reactive with TCRs that include V beta 14. The frequency of V beta 14+ T cells varies with CD4 and CD8 subset and is controlled by the H-2 genes.
Liao, N, Maltzman, J, RAULET, David H.
core  

Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses [PDF]

open access: yes, 2008
Alum is used as a vaccine adjuvant and induces T<sub>h</sub>2 responses and T<sub>h</sub>2-driven antibody isotype production against co-injected antigens.
A. S. McKee   +45 more
core   +1 more source

Function and mechanisms of T cells in the damage and repair of lung epithelial cells

open access: yes生物医学转化, 2023
Lung epithelial cells play a protective role in the respiratory system. However, various pathological factors such as infection, trauma, and inflammation can lead to damage to lung epithelial cells, causing lung diseases.
Liu Enzhuo, Liu Zhichun, Wen Zhenke
doaj   +1 more source

Transcriptomics reveals a distinct metabolic profile in T cells from severe allergic asthmatic patients

open access: yesFrontiers in Allergy, 2023
The reasons behind the onset and continuation of chronic inflammation in individuals with severe allergies are still not understood. Earlier findings indicated that there is a connection between severe allergic inflammation, systemic metabolic ...
Carmela Pablo-Torres   +14 more
doaj   +1 more source

Identification of a porcine liver eomes-high-T-bet-low NK cell subset that resembles human liver resident NK cells [PDF]

open access: yes, 2019
Natural killer (NK) cells are cells of the innate immunity and play an important role in the defense against viral infections and cancer, but also contribute to shaping adaptive immune responses. Long-lived tissue-resident NK cells have been described in
De Pelsmaeker, Steffi   +3 more
core   +2 more sources

Formation and phenotypic characterization of CD49a, CD49b and CD103 expressing CD8 T cell populations in human metastatic melanoma

open access: yesOncoImmunology, 2018
Integrins α1β1 (CD49a), α2β1 (CD49b) and αEβ7 (CD103) mediate retention of lymphocytes in peripheral tissues, and their expression is upregulated on tumor infiltrating lymphocytes (TIL) compared to circulating lymphocytes.
Marit M. Melssen   +10 more
doaj   +1 more source

Galangin ameliorates experimental autoimmune encephalomyelitis in mice via modulation of cellular immunity

open access: yesJournal of Immunotoxicology, 2021
Multiple sclerosis (MS) causes neurologic disabilities that effect musculature, sensory systems, and vision. This is largely due to demyelination of nerve fibers caused by chronic inflammation.
Kok-Tong Tan   +4 more
doaj   +1 more source

Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta [PDF]

open access: yes, 2007
The induction of regulatory T (T reg) cells holds considerable potential as a treatment for autoimmune diseases. We have previously shown that CD4(+)CD25(hi) T reg cells isolated from patients with active rheumatoid arthritis (RA) have a defect in their ...
Ehrenstein, MR, Mauri, C, Nadkarni, S
core  

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