Results 221 to 230 of about 1,131,184 (349)

Development of a novel in vitro micronucleus test using human induced pluripotent stem cell-derived T lymphocytes. [PDF]

Genes Environ
Kobayashi R, Sasaki K, Matsuyama R, Saito K, Kumagai A, Kitayama S, Kawai Y, Kaneko S.   +7 more
europepmc   +1 more source

T-Lymphocyte [PDF]

, 2020
openaire   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

mRNA-engineered T lymphocytes secreting bispecific T cell engagers with therapeutic potential in solid tumors. [PDF]

Front Immunol
Zagorac I, Ramírez-Fernández Á, Tapia-Galisteo A, Rubio-Pérez L, Gómez-Rosel M, Grau M, Rodríguez-Peralto JL, Álvarez-Vallina L, Blanco B.   +8 more
europepmc   +1 more source

T lymphocytes in psoriasis [PDF]

, 1995
Debets, J.E.M.A. (Reno), Hegmans, J.P.J.J. (Joost), Prens, E.P. (Errol)   +2 more
core   +1 more source

Studies of cytotoxic T lymphocytes and natural killer cells in relation to MHC class I presented peptides

, 1998
Lars Franksson
openalex  

CYP4X1/sEH‐Dependent Endocannabinoid Metabolism Drives Fibroblast‐Mediated Immunosuppression to Limit Immunotherapy in Colon Cancer

Advanced Science, EarlyView.
A proposed mechanism to explain the role of CYP4X1/sEH‐14,15‐EET‐EA system in colon cancer immune escape. 14,15‐EET‐EA, 14,15‐epoxyeicosatrienoic acid‐ethanolamide; sEH, soluble epoxide hydrolase; CYP4X1, cytochrome P450 4X1; GPR119, G‐protein coupled receptor 119; EGFR, epidermal growth factor receptor; Gs, Gαs subunit; cAMP, cyclic adenosine ...
Min Mo, Xuewei Chen, Yanzhuo Liu, Chenlong Wang, Xuehan Chen, Nan Zhang, Nan He, Ying Li, Jingyi Wang, Honglei Chen, Jing Yang   +10 more
wiley   +1 more source

Dormant Metastases Exhibit a Unique Phenotype Primarily Promoted by the Ch25h Gene and Are Maintained in Dormancy by T Lymphocytes. [PDF]

MedComm (2020)
Chamorro V, Algarra I, Sanz V, Pulido M, Romero I, Chico E, Millán M, Escaño-Maestre M, Botella P, Linares I, García-Lora ÁM.   +10 more
europepmc   +1 more source

Single‐Cell Transcriptome Atlas Reveals the Underlying Mechanism of Kynurenic Acid in the Regulation of Tumor Immune Microenvironment in Glioblastoma

Advanced Science, EarlyView.
KYNA regulates the tumor immune microenvironment in glioblastoma. KYNA reprograms the balance between T cell exhaustion and activation to suppress glioblastoma progression through inhibiting exhaustion‐associated markers (such as PD‐1, LAG3, and TOX) and enhancing immune activation and cytotoxicity markers including granzymes GZMA and GZMB.
Di Chen, Liming Sun, Jiajun Chen, Zi Ye, Xuqiang Zhu, Hongjiang Li, Lixin Wu, Guohua Zhao, Qinghao Zhang, Guangyi Jiang, Yuchen Ji, Yake Xue, Hongwei Li, Ruokun Chen, Hongwei Zheng, Rong Zeng, Dongming Yan, Yong Zhang, Xueyuan Li, Jing Yan   +19 more
wiley   +1 more source

Actin conformation dynamics precede force generation in cytotoxic T lymphocytes

Lippert A, Rochussen A, Kebabci A, Winkel A, Franze K, Fletcher D, Griffiths G.   +6 more
europepmc   +2 more sources