Results 71 to 80 of about 12,899,769 (365)

Imperial strategy of cancer cells through mitochondrial transfer

Molecular Oncology, EarlyView.
Cangkrama et al. demonstrated that cancer cells donate their mitochondria to fibroblasts through mitochondrial transfer, reprogramming them into ‘MitoCAF’. Likewise, our group has identified mitochondrial transfer from cancer cells to tumor infiltrating lymphocytes, resulting in mitochondrial ‘hijack’ and impaired antitumor immunity.
Takamasa Ishino, Yosuke Togashi
wiley   +1 more source

Inflammatory and immune variables as predictors of survival in dogs with myxomatous mitral valve disease

BMC Veterinary Research
Background We aimed to investigate the association between selected inflammatory and immune variables and survival of dogs with myxomatous mitral valve disease (MMVD).
Martina Cimerman, Natalia Druzhaeva, Alenka Nemec Svete, Melita Hajdinjak, Katka Pohar, Alojz Ihan, Aleksandra Domanjko Petrič   +6 more
doaj   +1 more source

Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth

Journal of Experimental Medicine, 1986
This study examines the potential role of transforming growth factor beta (TGF-beta) in the regulation of human T lymphocyte proliferation, and proposes that TGF-beta is an important autoregulatory lymphokine that limits T lymphocyte clonal expansion ...
J. Kehrl, L. Wakefield, A. Roberts, S. Jakowlew, M. Alvarez-Mon, R. Derynck, M. Sporn, A. Fauci   +7 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Decreased T Cell Levels in Critically Ill Coronavirus Patients: Single-Center, Prospective and Observational Study

Journal of Inflammation Research, 2021
Jingjing Xu,1 Zhiyu Liu,2 Haitao Liu,1 Yunpeng Luo,3 Kai Kang,3 Xueting Li,1 Wei Yang,3 Dongsheng Fei,3 Changsong Wang,1,3 Kaijiang Yu3 1Department of Critical Care Medicine, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province ...
Xu J, Liu Z, Liu H, Luo Y, Kang K, Li X, Yang W, Fei D, Wang C, Yu K   +9 more
doaj  

Sex differences of subpopulation composition of lymphocytes in the peripheral blood in experimental acute and chronic ulcerative colitis

Медицинская иммунология, 2020
We studied sex differences lymphocytes subpopulations of peripheral blood in adult C57Bl/6 mice during acute and chronic colitis, induced with 1% DSS. We measured subpopulations of lymphocytes with flow cytometry.
O. V. Makarova, E. A. Postovalova, Yu. Gao, M. T. Dobrynina   +3 more
doaj   +1 more source

Lymphocytic Colitis With Enterocolic Lymphocytic Phlebitis

ACG Case Reports Journal
ABSTRACT Enterocolic lymphocytic phlebitis is a rare lymphocytic vasculitis afflicting the gastrointestinal veins without involving the arterial system. Lymphocytic colitis is a more common pathology described as lymphocytic inflammation of the colonic epithelium. Concurrence of both these pathologies is extremely rare.
Nadeem, Ahmed, Naseem, Zehra, Li (Xue Jing), Claire, Shah, Fatima Zehra, David, Aidan, Scudiere, Jennifer, Jondle, Daniel, Fulmer, Clifton, Mansoor, Emad, David, Joseph   +9 more
openaire   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

МЕСТО РРСС В НОЗОПРОФИЛЕ ИНФЕКЦИОННОЙ ПАТОЛОГИИ СВИНЕЙ В РОСТОВСКОЙ ОБЛАСТИ

Ветеринарная патология, 2010
Infectious pathology of pigs in the Rostov region is represented mainly bacterial diseases (52,8% of the total infectious diseases). However, the bacteria, as is usually secondary pathogens to cause clinical picture against viral disease.

doaj  

Impacts of tacrolimus and glucocorticoids on peripheral blood T and B lymphocyte subsets in myasthenia gravis

Frontiers in Immunology
BackgroundThis study aimed to investigate the impact of tacrolimus on peripheral T and B lymphocyte subsets in myasthenia gravis (MG) patients compared to glucocorticoid treatment.MethodsThis study retrospectively included MG patients at the First ...
Xuan Wu, Xuan Wu, Wei Chen, Wei Chen, Huanhuan Song, Guorong Xu, Guorong Xu   +6 more
doaj   +1 more source