Results 101 to 110 of about 28,279,407 (312)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Course Catalogue of the Massachusetts Institute of Technology 2002-2003 [PDF]
, 2002 Massachusetts Institute of Technology Bulletin 2002-2003. Courses and Degree Programs Issue. Includes general information on the Institute; campus life; undergraduate and graduate education; academic procedures and institute regulations ...
Massachusetts Institute of Technology
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
General Electric Atomic Power Reports [PDF]
, 1964 From introduction: "Summary report of the 1000 MWe Boiling Water Reactor Plant Feasibility Study performed by the General Electric Company.
General Electric Company
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Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
CRISPR in Targeted Therapy and Adoptive T Cell Immunotherapy for Hepatocellular Carcinoma
Journal of Hepatocellular CarcinomaFahreddin Palaz,1,2 Mehmet Ozsoz,3 Ali Zarrinpar,4,5 Ilyas Sahin5,6 1Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; 2Faculty of Medicine, Hacettepe University, Ankara, Turkey; 3Department of Biomedical ...
Palaz F, Ozsoz M, Zarrinpar A, Sahin I
doaj
The Technology Architectural Record [PDF]
, 1907 Publication of the Massachusetts Institute of Technology Architectural Society. Volume 1.
Massachusetts Institute of Technology. Department of Architecture +1 more
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Measuring built environment technology awareness using time-series analysis
, 2021 Thesis: M.C.P., Massachusetts Institute of Technology, Department of Urban Studies and Planning, February, 2021Thesis: S.M. in Real Estate Development, Massachusetts Institute of Technology, Program in Real Estate Development in conjunction with the ...
Wang, Yuehan, M.C.P. Massachusetts Institute of Technology.
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source