A self-degradable hydrogel sensor for a nerve agent tabun surrogate through a self-propagating cascade [PDF]
Cell Reports Physical Science, 2021 Summary: Nerve agents that irreversibly deactivate the enzyme acetylcholinesterase are extremely toxic weapons of mass destruction. Thus, developing methods to detect these lethal agents is important.
Doo-Hee Lee +5 more
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A Comparison of the Neuroprotective and Reactivating Efficacy of a Novel Bispyridinium Oxime K870 with Commonly Used Pralidoxime and the Oxime HI-6 in Tabun-Poisoned Rat [PDF]
Acta Medica, 2021 Aim: The comparison of neuroprotective and central reactivating effects of the oxime K870 in combination with atropine with the efficacy of standard antidotal treatment in tabun-poisoned rats.
Jiří Kassa +5 more
doaj +2 more sources
Ethnomathematics on Dayak Tabun Traditional Tools for School Mathematics Learning
International Journal of Trends in Mathematics Education Research, 2019 The purpose of this study was to describe ethnomathematics on Dayak Tabun traditional tools in school mathematics learning. This study uses a qualitative approach, with descriptive research methods.
Hartono Hartono, Marhadi Saputro
doaj +4 more sources
The Influence of the Time of Antidotal Treatment Administration on Its Effectiveness Against Tabun-Induced Poisoning in Mice [PDF]
Acta Medica, 2004 Summary: 1. The influence of the time of administration of antidotal treatment consisting of anticholinergic drug (atropine) and oxime (pralidoxime, obidoxime, HI-6 or trimedoxime) on its effectiveness to eliminate tabun-induced lethal effects was ...
Jiří Kassa
doaj +2 more sources
The Evaluation of the Reactivating and Neuroprotective Efficacy of Two Newly Prepared Bispyridinium Oximes (K305, K307) in Tabun-Poisoned Rats—A Comparison with Trimedoxime and the Oxime K203 [PDF]
Molecules, 2017 The ability of two newly developed oximes (K305, K307) to protect tabun-poisoned rats from tabun-induced inhibition of brain acetylcholinesterase, acute neurotoxic signs and symptoms and brain damage was compared with that of the oxime K203 and ...
Jiri Kassa +6 more
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Comparison of Effects of Different Antidotes on Tabun-Induced Cognitive Impairment in Rats Using Water Maze [PDF]
Acta Medica, 2006 In the past, scientists focused on the development of antidotes (mainly anticholinergics in combination with reactivators of inhibited acetylcholinesterase – oximes) to increase the number of surviving nerve agent-intoxicated individuals.
Gabriela Kunešová, Jiří Kassa
doaj +2 more sources
A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase [PDF]
BMC Pharmacology and Toxicology, 2018 Background Based on in vitro and in vivo rat experiments, the newly developed acetylcholinesterase (AChE) reactivator, K203, appears to be much more effective in the treatment of tabun poisonings than currently fielded oximes.
Kamil Kuca +12 more
doaj +2 more sources
Effect of Methoxime Combined with Anticholinergic, Anticonvulsant or Anti-HCN Drugs in Tabun-Poisoned Mice [PDF]
Acta Medica, 2003 The effect of methoxime combined with a) atropine, b) benactyzine, c) atropine and natrium thiosulphate, d) atropine and diazepam on antidotal treatment effectiveness was studied in tabun-poisoned mice.
Lucie Ševelová, Josef Vachek
doaj +2 more sources
Qualitative Analysis of Novel Flavonoid Adducts from Nerve Agent Tabun-Exposed Arabidopsis thaliana (L.) Based on Quadrupole–Time of Flight Mass Spectrometry [PDF]
Molecules, 2023 Flavonoids are a kind of secondary metabolite which widely exist in plants. They contain a lot of active hydroxyls, which can react with toxic chemicals to produce potential exposure biomarkers.
Zhongfang Xing +8 more
doaj +2 more sources
The Evaluation of the Potency of Newly Developed Oximes (K727, K733) and Trimedoxime to Counteract Acute Neurotoxic Effects of Tabun in Rats [PDF]
Acta Medica, 2016 Aim: The ability of two newly developed oximes (K727, K733) to reduce tabun-induced acute neurotoxic signs and symptoms was evaluated and compared with currently available trimedoxime in rats.
Jiří Kassa +2 more
doaj +2 more sources