A self-degradable hydrogel sensor for a nerve agent tabun surrogate through a self-propagating cascade [PDF]
Cell Reports Physical Science, 2021 Summary: Nerve agents that irreversibly deactivate the enzyme acetylcholinesterase are extremely toxic weapons of mass destruction. Thus, developing methods to detect these lethal agents is important.
Doo-Hee Lee +5 more
doaj +2 more sources
Qualitative Analysis of Novel Flavonoid Adducts from Nerve Agent Tabun-Exposed Arabidopsis thaliana (L.) Based on Quadrupole–Time of Flight Mass Spectrometry [PDF]
Molecules, 2023 Flavonoids are a kind of secondary metabolite which widely exist in plants. They contain a lot of active hydroxyls, which can react with toxic chemicals to produce potential exposure biomarkers.
Zhongfang Xing +8 more
doaj +2 more sources
Influence of Experimental End Point on the Therapeutic Efficacy of Essential and Additional Antidotes in Organophosphorus Nerve Agent-Intoxicated Mice [PDF]
Toxics, 2022 The therapeutic efficacy of treatments for acute intoxication with highly toxic organophosphorus compounds, called nerve agents, usually involves determination of LD50 values 24 h after nerve agent challenge without and with a single administration of ...
Jiri Kassa +4 more
doaj +2 more sources
Anticholinergic Drugs – Functional Antidotes for the Treatment of Tabun Intoxication [PDF]
Acta Medica, 2004 Summary: 1. To study the influence of antidotes on tabun-induced neurotoxicity, the rats were injected intramuscularly with organophosphate tabun (LD50).
Gabriela Krejčová, Jiří Kassa
doaj +3 more sources
Highly precise optical detection of mass destruction nerve agents based on photonic crystal fibers [PDF]
Scientific ReportsNerve agents such as Sarin, Soman, and Tabun are among the most lethal chemical warfare agents, classified as mass destruction agents due to their extreme toxicity and rapid disruption of the nervous system.
Mohamed Z. Elabdein +3 more
doaj +2 more sources
Acta Medica, 2021 Aim: The comparison of neuroprotective and central reactivating effects of the oxime K870 in combination with atropine with the efficacy of standard antidotal treatment in tabun-poisoned rats.
Jiří Kassa +5 more
doaj +1 more source
Protective effect of HI-6 and trimedoxime combination in mice acutely poisoned with tabun, dichlorvos or heptenophos [PDF]
Acta Veterinaria, 2012 The aim of this study was to compare the protective effect of two individual oximes (HI-6 and trimedoxime) with their combination in mice acutely poisoned with tabun, dichlorvos or heptenophos.
Antonijević Biljana +2 more
doaj +1 more source
Chemical Weapons in the Iran-Iraq War (1980-1988) Iraq Preparing for Chemical War
Вестник войск РХБ защиты, 2023 The Iraqis became the first nation to use chemical weapons on the modern battlefield during the IranIraq War (1980-1988). There are no general reviews and research available on this issue in Russian.
M. V. Supotnitskiy +2 more
doaj +1 more source
In silico studies in probing the role of kinetic and structural effects of different drugs for the reactivation of tabun-inhibited AChE. [PDF]
PLoS ONE, 2013 We have examined the reactivation mechanism of the tabun-conjugated AChE with various drugs using density functional theory (DFT) and post-Hartree-Fock methods. The electronic environments and structural features of neutral oximes (deazapralidoxime and 3-
Rabindranath Lo +4 more
doaj +1 more source
Chemical Weapons in the Iran-Iraq War (1980–1988) 3. Medical Consequences of Chemical Warfare
Вестник войск РХБ защиты, 2023 The third article in the series is dedicated to the medical consequences of the chemical warfare between Iran and Iraq during the war (1980–1988). The UN official documents and materials, declassified CIA documents, as well as other open Western and ...
M. V. Supotnitskiy +2 more
doaj +1 more source