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Toxicokinetics of tabun enantiomers in anaesthetized swine after intravenous tabun administration
Toxicology Letters, 2010In the present study, we report the first in vivo toxicokinetic study of tabun (O-ethyl-N,N-dimethylphosphoramidocyanidate). The toxicokinetics of the enantiomers of tabun were investigated in anesthetized swine after intravenous administration of 3xLD(50) (161.4mug/kg) tabun.
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Effective bisquaternary reactivators of tabun-inhibited AChE
Journal of Applied Toxicology, 2005AbstractTwo cholinesterase reactivators (K074 and K075) were synthesized and their reactivation efficacy against tabun‐inhibited acetylcholinesterase of the rat brain was tested in vitro. Comparing this efficacy showed that commonly used oximes (pralidoxim, obidoxime and HI‐6) were practically without reactivation potency.
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Effect of pyridostigmine pretreatment on cardiorespiratory function in tabun poisoning
Human and Experimental Toxicology, 19951 The effect of pyridostigmine on cardiorespiratory func tion after oxime+atropine injection was investigated in tabun poisoned guinea-pigs and without tabun poisoning. 2 The trachea, a carotid artery and jugular vein were can nulated in female urethane-anaesthetised Pirbright white guinea-pigs.
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Novel and selective detection of Tabun mimics
Chem. Commun., 2014Detection of nerve agent-related molecules based on BODIPY–salicylaldehyde oxime conjugation was studied.
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