Results 101 to 110 of about 961 (162)

Changes in Active Site Loop Conformation Relate to the Transition toward a Novel Enzymatic Activity. [PDF]

open access: yesJACS Au
Jacquet P   +8 more
europepmc   +1 more source

Toxicokinetics of tabun enantiomers in anaesthetized swine after intravenous tabun administration

Toxicology Letters, 2010
In the present study, we report the first in vivo toxicokinetic study of tabun (O-ethyl-N,N-dimethylphosphoramidocyanidate). The toxicokinetics of the enantiomers of tabun were investigated in anesthetized swine after intravenous administration of 3xLD(50) (161.4mug/kg) tabun.
Horst Thiermann, Franz Worek
exaly   +3 more sources

Effective bisquaternary reactivators of tabun-inhibited AChE

Journal of Applied Toxicology, 2005
AbstractTwo cholinesterase reactivators (K074 and K075) were synthesized and their reactivation efficacy against tabun‐inhibited acetylcholinesterase of the rat brain was tested in vitro. Comparing this efficacy showed that commonly used oximes (pralidoxim, obidoxime and HI‐6) were practically without reactivation potency.
Kamil Kuca   +2 more
exaly   +3 more sources

Effect of pyridostigmine pretreatment on cardiorespiratory function in tabun poisoning

Human and Experimental Toxicology, 1995
1 The effect of pyridostigmine on cardiorespiratory func tion after oxime+atropine injection was investigated in tabun poisoned guinea-pigs and without tabun poisoning. 2 The trachea, a carotid artery and jugular vein were can nulated in female urethane-anaesthetised Pirbright white guinea-pigs.
Franz Worek, L Szinicz
exaly   +3 more sources

Novel and selective detection of Tabun mimics

Chem. Commun., 2014
Detection of nerve agent-related molecules based on BODIPY–salicylaldehyde oxime conjugation was studied.
Jang, YJ Jang, Yoon Jeong   +5 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy