Results 111 to 120 of about 961 (162)

Genotoxicity of the phosphoramidate agent tabun (GA)

Toxicology, 1994
Five mutagenicity tests were performed on Agent GA (Tabun, phosphoramidocyanidic acid, dimethyl-, ethyl ester) as part of a program to demilitarize chemical warfare agents. GA was mutagenic in Salmonella spp. assays with S-9 and it was a direct-acting mutagen to mouse lymphoma cells.
B W, Wilson, T G, Kawakami, N, Cone, J D, Henderson, L S, Rosenblatt, M, Goldman, J C, Dacre   +6 more
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Toxogonin in Sarin, Soman and Tabun poisoning

Biochemical Pharmacology, 1965
The oximes P2S, TMB-4 and Toxogonin have been tested as reactivators of Sarin and Tabun inhibited acetylcholinesterase. The protective effect of the oximes has been studied on atropinized mice in experimental Sarin, Soman and Tabun poisoning. Toxogonin is a better reactivator than P2S and comparable to TMB-4. In the presence of 10 mg/kg atropine (i.p.)
E, HEILBRONN, B, TOLAGEN
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INHIBITION OF THE ESTERATIC ACTIVITY OF THROMBIN BY SARIN AND TABUN

Canadian Journal of Biochemistry and Physiology, 1959
Isopropyl methylphosphonofluoridate (sarin) and ethyl N,N-dimethylphosphoramidocyanidate (tabun) have been found to inhibit the esteratic activity of thrombin towards the substrate p-toluenesulphonyl-L-arginine methyl ester. The rate of inhibition is markedly dependent on pH and is greatest in alkaline solutions.
J, SHUSTER, J F, SCAIFE, G A, GRANT
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THE INDUCTION OF METHEMOGLOBINEMIA AS AN ADJUNCT TO THERAPY FOR TABUN POISONING

Canadian Journal of Biochemistry and Physiology, 1960
The protective and therapeutic effectiveness of p-aminopropiophenone (PAPP) against tabun poisoning in the rat has been examined. The relationship between dosage of PAPP and percentage of methaemoglobin in the blood of the rat has been determined.Treatment of rats with PAPP both alone and in conjunction with atropine gave no evidence of protection ...
I W, COLEMAN, P E, LITTLE, G A, GRANT
openaire   +2 more sources

Synthesis of a New Reactivator (I) of Tabun‐Inhibited Acetylcholinesterase.

ChemInform, 2003
Synthesis of a new asymmetric bisquaternary reactivator of tabun-inhibited acetylcholinesterase-1-(4-hydroxyiminomethylpyridinium)-4-(4-carbamoylpyridinium) butane dibromide is described. Reactivation potency of this oxime is compared to the currently used reactivators-pralidoxime, obidoxime and H-oxime HI-6.
Kamil, Kuca, Jirí, Bielavský, Jirí, Cabal, Jirí, Kassa   +3 more
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STUDIES ON THE ENZYMATIC HYDROLYSIS OF SARIN AND TABUN

Canadian Journal of Biochemistry and Physiology, 1958
The enzymes which hydrolyze isopropyl methylphosphonofluoridate (sarin) and ethyl N, N-dimethylphosphoramidocyanidate (tabun) have been studied. Michaelis–Menten constants and activation energies have been estimated and enzyme stability has been studied. The distribution of the enzymes in mammalian tissues has been examined.
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Sarin, Soman, Tabun und VX

Notfall & Rettungsmedizin, 2002
Lange Zeit war ein chemischer Kampfmittelangriff ein militarisches Szenario. Spatestens seit der Attacke mit Sarin auf die Tokioter U-Bahn im Jahre 1995 durch den Aum-Shinrikyo-Kult werden zivile Kampfstoffeinsatze in den Szenarien von vielen Katastrophenplanern mit einbezogen.
T. Bey, F. G. Walter
openaire   +1 more source

The Tabun Cave and Paleolithic Man in the Levant

Science, 1982
Recent excavations at the deeply stratified Late Pleistocene cave site of Tabun on Mount Carmel have yielded a long sequence of Middle and Lower Paleolithic industries and associated geological and environmental evidence that has important implications for the understanding of man's cultural and biological development in that period.
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A Reassessment of the Tabun C2 Mandible

2005
As recently as just over a decade ago, a reasonable case could be made that modern humans initially appeared throughout the Old World, essentially contemporaneously, between 40 ka and 30 ka (e.g., Wolpoff 1980; Smith 1985). Objections to such an interpretation were numerous and grounded in various lines of evidence (e.g., Howells 1976; Stringer 1978 ...
Rolf M. Quam, Fred H. Smith
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Tabun-Khara-Obo, Mongolia

2019
The Tabun-Khara-Obo impact crater is situated in a remote part of the eastern Gobi Desert, about 470 km southeast of Ulaanbaatar, and it interrupts a northeast–southwest-striking sedimentary massif that is deeply etched by prevailing winds.
Goro Komatsu, Alessandro Coletta, Maria Libera Battagliere, Maria Virelli   +3 more
openaire   +1 more source